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. 2022 Sep;67(9):4317-4320.
doi: 10.1007/s10620-022-07564-y. Epub 2022 Jul 5.

IgG4-Related Disease with Hypophysitis and Cholangitis as the Main Manifestations

Yan Huang  1 , Yu Meng Liu  1 , Zhong Hua Lu  2 , Jian He Gan  1 , Wei Feng Zhao  1 , Xiao Ping Huang  3
Affiliations

IgG4-Related Disease with Hypophysitis and Cholangitis as the Main Manifestations

Yan Huang et al. Dig Dis Sci. 2022 Sep.
No abstract available

Keywords: Cholangiocarcinoma; IgG4-related disease; IgG4-related hypophysitis; IgG4-related sclerosing cholangitis.

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Conflict of interest statement

The authors declare that they have no competing interests and approved the final manuscript.

Figures

Fig. 1
Fig. 1
Abdominal magnetic resonance imaging (MRI) + magnetic resonance cholangiopancreatography (MRCP). a Intrahepatic dilatation of bile duct with left hepatic pericholangitis, stenosis of lower common bile duct with dilatation of upper duct, and the head of the pancreas augment and lymph nodes around the head, in the abdominal cavity, and under the right diaphragm were enlarged. b One year after treatment, the volume of the left lobe of the liver was reduced, and the dilated left bile duct and the bile duct in the left lobe of liver were significantly improved. No other abnormality was found
Fig. 2
Fig. 2
Pituitary MRI. a The upper end of the pituitary stalk was thickened, the high signal in the posterior pituitary disappeared, and the enhancement degree of the pituitary decreased. b One year after treatment, the pituitary stalk was thinner than before, and the signal of other pituitary glands was similar
Fig. 3
Fig. 3
Liver biopsy pathology. a The inflammation in the portal tract was more severe than that in the hepatic lobule, and abundant infiltration of plasma cells and bile duct injury were found. b There were concentric collagenous deposition around interlobular bile duct, and obvious interlobular hepatitis. c A large number of plasma cells and IgG4-positive plasma cells > 50 per high-power field; d Portal lymph nodes showed a large amount of plasma cell infiltration on MUM1 immunohistochemistry and IgG4-positive plasma cells > 50 per high-power field
See this image and copyright information in PMC

References

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