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Comment
. 2022 Jul 5;7(1):211.
doi: 10.1038/s41392-022-01088-7.

SARS-CoV-2 Omicron: a new challenge for pandemic and vaccine

Xiantao Zhang  1 , Hui Zhang  1 , Xin He  2
Affiliations
Comment

SARS-CoV-2 Omicron: a new challenge for pandemic and vaccine

Xiantao Zhang et al. Signal Transduct Target Ther. .
No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Omicron and its subvariants evolved to be adaptation and balance between transmission, pathogenicity and immune escape. Compared to early VOCs, such as D614G or Delta strains (bottom part), Omicron and its subvariants have more than thirty mutations in the Spike (top part). The Omicron-infected and replicated more in the upper respiratory tract, but the early VOCs attacked the lung seriously. The new variant Omicrons have an enhanced infectivity and immune evasion capabilities, with low inflammation and mild symptoms
See this image and copyright information in PMC

Comment on

  • Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 Omicron.
    Shuai H, Chan JF, Hu B, Chai Y, Yuen TT, Yin F, Huang X, Yoon C, Hu JC, Liu H, Shi J, Liu Y, Zhu T, Zhang J, Hou Y, Wang Y, Lu L, Cai JP, Zhang AJ, Zhou J, Yuan S, Brindley MA, Zhang BZ, Huang JD, To KK, Yuen KY, Chu H. Shuai H, et al. Nature. 2022 Mar;603(7902):693-699. doi: 10.1038/s41586-022-04442-5. Epub 2022 Jan 21. Nature. 2022. PMID: 35062016

References

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