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Editorial
. 2022 Jul 6;12(7):1615-1616.
doi: 10.1158/2159-8290.CD-22-0472.

IFNα Potentiates Immune-Checkpoint Blockade by Rewiring Metabolic Cross-talk

Kung-Chi Kao #  1   2 , Alison Jaccard #  1   2 , Ping-Chih Ho  1   2
Affiliations
Editorial

IFNα Potentiates Immune-Checkpoint Blockade by Rewiring Metabolic Cross-talk

Kung-Chi Kao et al. Cancer Discov. .

Abstract

In this issue, Hu and colleagues unveil that IFNα administration combined with anti-PD-1 therapy can potentiate murine and human CD8+ T-cell antitumor response in hepatocellular carcinoma, highlighting a novel therapeutic strategy for hepatocellular carcinoma. See related article by Hu et al., p. 1718 (6) .

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