Could Blood Hexosylsphingosine Be a Marker for Parkinson's Disease Linked with GBA1 Mutations?
- PMID: 35792565
- DOI: 10.1002/mds.29132
Could Blood Hexosylsphingosine Be a Marker for Parkinson's Disease Linked with GBA1 Mutations?
Comment in
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Reply to: "Overlapping Ranges in Levels Indicate That Hexosylsphingosine Is Not a Clinically Relevant Biomarker for GBA1-Associated Parkinson's Disease".Mov Disord. 2022 Aug;37(8):1781-1782. doi: 10.1002/mds.29131. Mov Disord. 2022. PMID: 35980034 Free PMC article. No abstract available.
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Reply to: "Could Blood Hexosylsphingosine Be a Marker for Parkinson's Disease Linked with GBA1 Mutations"?Mov Disord. 2022 Aug;37(8):1782. doi: 10.1002/mds.29136. Mov Disord. 2022. PMID: 35980035 No abstract available.
Comment on
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Plasma Glucosylsphingosine in GBA1 Mutation Carriers with and without Parkinson's Disease.Mov Disord. 2022 Feb;37(2):416-421. doi: 10.1002/mds.28846. Epub 2021 Nov 6. Mov Disord. 2022. PMID: 34741486 Free PMC article.
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No Evidence That Glucosylsphingosine Is a Biomarker for Parkinson's Disease: Statistical Differences Do Not Necessarily Indicate Biological Significance.Mov Disord. 2022 Mar;37(3):653. doi: 10.1002/mds.28935. Epub 2022 Jan 24. Mov Disord. 2022. PMID: 35075696 Free PMC article. No abstract available.
References
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- Surface M, Balwani M, Waters C, et al. Plasma glucosylsphingosine in GBA1 mutation carriers with and without Parkinson's disease. Mov Disord 2022;37(2):416-421. https://doi.org/10.1002/mds.28846
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- Gleason A, Tayebi N, Lopez G, Sidransky E. No evidence that glucosylsphingosine is a biomarker for Parkinson's disease: statistical differences do not necessarily indicate biological significance. Mov Disord 2022;37(3):653. https://doi.org/10.1002/mds.28935
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- Pchelina S, Emelyanov A, Baydakova G, et al. Oligomeric alpha-synuclein and glucocerebrosidase activity levels in GBA-associated Parkinson's disease. Neurosci Lett 2017;636:70-76. https://doi.org/10.1016/j.neulet.2016.10.039
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- Pchelina S, Baydakova G, Nikolaev M, et al. Blood lysosphingolipids accumulation in patients with parkinson's disease with glucocerebrosidase 1 mutations. Mov Disord 2018;33(8):1316-1321. https://doi.org/10.1002/mds.27393
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- Polo G, Burlina AP, Ranieri E, et al. Plasma and dried blood spot lysosphingolipids for the diagnosis of different sphingolipidoses: a comparative study. Clin Chem Lab Med 2019;57(12):1863-1874. https://doi.org/10.1515/cclm-2018-1301
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