Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2022 Jul 5;34(7):940-942.
doi: 10.1016/j.cmet.2022.06.005.

A neuroimmunometabolic view on the cephalic phase of insulin release

Gitalee Sarker  1 , Ana I Domingos  2
Affiliations
Free article
Comment

A neuroimmunometabolic view on the cephalic phase of insulin release

Gitalee Sarker et al. Cell Metab. .
Free article

Abstract

The cephalic phase of insulin secretion (CPIS) plays a crucial role in glucose homeostasis. However, the neural basis of CPIS and its overall relevance to metabolic health are poorly understood. Here, we preview the findings of Wiedemann et al. (2022) that address the role of IL-1β in the integration of neuro-mediated insulin release following cephalic stimulation and CPIS dysregulation in obesity.

PubMed Disclaimer

Conflict of interest statement

Declaration of interests The authors declare no competing interests.

Comment on

  • The cephalic phase of insulin release is modulated by IL-1β.
    Wiedemann SJ, Trimigliozzi K, Dror E, Meier DT, Molina-Tijeras JA, Rachid L, Le Foll C, Magnan C, Schulze F, Stawiski M, Häuselmann SP, Méreau H, Böni-Schnetzler M, Donath MY. Wiedemann SJ, et al. Cell Metab. 2022 Jul 5;34(7):991-1003.e6. doi: 10.1016/j.cmet.2022.06.001. Epub 2022 Jun 23. Cell Metab. 2022. PMID: 35750050

Publication types

LinkOut - more resources