Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Nov;10(6):1407-1414.
doi: 10.1007/s43390-022-00533-5. Epub 2022 Jul 6.

Lordosis loss in degenerative spinal conditions

Affiliations

Lordosis loss in degenerative spinal conditions

Will K M Kieffer et al. Spine Deform. 2022 Nov.

Abstract

Purpose: To establish whether common degenerative lumbar spine conditions have a predictable sagittal profile and associated range of lordosis. The spinopelvic balance of a normal population and normal ranges are well described in the literature. There is also evidence that certain degenerative conditions can lead to a preponderance of loss of lordosis at specific spinal levels. There is limited literature on the range and magnitude of loss of lordosis for known degenerative lumbar spine pathologies.

Methods: A retrospective analysis of prospectively obtained radiographs from a dual surgeon database was performed and imaging analysed for spinopelvic parameters. Degenerative conditions studied were; Lumbar degenerative spondylolisthesis (L3/4 and L4/5 analysed separately), L5/S1 degenerative disc disease, L5/S1 isthmic spondylolisthesis. Pelvic incidence, sacral slope, pelvic tilt, segmental and global lumbar lordosis, vertebral lordosis and lumbar vertical axis were measured.

Results: The range of change in segmental lordosis was normally distributed for all studied degenerative spinal conditions except L5/S1 isthmic spondylolisthesis. L5/S1 degenerative disc disease affected younger adults (mean age 37), whilst degenerative spondylolisthesis at L3/4 and L4/5 affected older adults (mean ages 69.5 and 68.9 respectively). Removing an outlying high-grade L5/S1 isthmic spondylolisthesis made the data distribution approach a normal distribution.

Conclusion: Most degenerative spinal pathologies cause a normally distributed spectrum of deformity which should be addressed and corrected with a tailored, individualised surgical plan for each patient. Universal treatment recommendations should be interpreted with caution.

Keywords: Degeneration; Degenerative spinal conditions; Lordosis; Lumbar spine; Sagittal balance; Spinal alignment; Spinopelvic parameters; Spondylolisthesis.

PubMed Disclaimer

References

    1. Vaz G, Roussouly P, Berthonnaud E et al (2002) Sagittal morphology and equilibrium of pelvis and spine. Eur Spine J 11(1):80–87. https://doi.org/10.1007/s005860000224 - DOI - PubMed
    1. Labelle H, Roussouly P, Berthonnaud E et al (2005) The importance of spino-pelvic balance in L5–s1 developmental spondylolisthesis: a review of pertinent radiologic measurements. Spine (Phila Pa 1976) 30(6 Suppl):S27-34. https://doi.org/10.1097/01.brs.0000155560.92580.90 - DOI
    1. Rothenfluh DA, Mueller DA, Rothenfluh E et al (2015) Pelvic incidence-lumbar lordosis mismatch predisposes to adjacent segment disease after lumbar spinal fusion. Eur Spine J 24(6):1251–1258. https://doi.org/10.1007/s00586-014-3454-0 (Epub 2014 Jul 14) - DOI - PubMed
    1. Damasceno LHF, Catarin SRG, Campos AD et al (2006) Lumbar lordosis: a study of angle values and of vertebral bodies and intervertebral discs role. Acta Ortopéd Brasileira 14(4):193–198 - DOI
    1. Pesenti S, Lafage R, Stein D et al (2018) The amount of proximal lumbar lordosis is related to pelvic incidence. Clin Orthop Relat Res 476(8):1603–1611. https://doi.org/10.1097/CORR.0000000000000380 - DOI - PubMed - PMC