Non-toxigenic Corynebacterium diphtheriae in hallux ulceration
- PMID: 35797309
- DOI: 10.3855/jidc.16153
Non-toxigenic Corynebacterium diphtheriae in hallux ulceration
Abstract
Introduction: Toxigenic Corynebacterium diphtheriae causes classical diphtheria. Skin infections by toxigenic or non-toxigenic Corynebacterium diphtheriae are prevalent in the tropics but are rarely reported.
Case presentation: We report the identification of a non-toxigenic Corynebacterium diphtheriae (biovar Gravis) isolate in a 52-year-old Cambodian male. The patient presented purulent and non-healing ulcerations on the right hallux. The wound has healed after 7 days of antibiotic therapy with a favourable outcome.
Conclusions: This case represents, to our knowledge, the first report of Corynebacterium diphtheriae in Cambodia in the last 10 years, and highlights the lack of diagnosis and notifications of diphtheria. It is important to raise awareness among clinicians and to set up diphtheria surveillance in Cambodia.
Keywords: Cambodia; Corynebacterium diphtheriae; hallux ulceration.
Copyright (c) 2022 Gauthier Delvallez, Edgar Badell, Sokleaph Cheng, Soda Meng, Vivandet Tong, Judy Norman, Julie Toubiana, Koen Vandelannoote, Anne-Laure Bañuls, Mallorie Hide, Sylvain Brisse.
Conflict of interest statement
No Conflict of Interest is declared
Similar articles
-
Case Report: Bloodstream Infection with Toxigenic Corynebacterium diphtheriae and Gram-Negative Sepsis in a Child with Burns.Am J Trop Med Hyg. 2022 Aug 29;107(4):930-933. doi: 10.4269/ajtmh.21-1233. Print 2022 Oct 12. Am J Trop Med Hyg. 2022. PMID: 36037863 Free PMC article.
-
[Screening of Corynebacterium diphtheriae, Corynebacterium ulcerans and Corynebacterium pseudotuberculosis in throat swab specimens of children with upper respiratory tract infections].Mikrobiyol Bul. 2017 Jul;51(3):209-219. doi: 10.5578/mb.57400. Mikrobiyol Bul. 2017. PMID: 28929958 Turkish.
-
The changing epidemiology of diphtheria in the United Kingdom, 2009 to 2017.Euro Surveill. 2020 Mar;25(11):1900462. doi: 10.2807/1560-7917.ES.2020.25.11.1900462. Euro Surveill. 2020. PMID: 32209165 Free PMC article.
-
Misidentification of toxigenic Corynebacterium diphtheriae as a Corynebacterium species with low virulence in a child with endocarditis.J Clin Microbiol. 1996 May;34(5):1275-6. doi: 10.1128/jcm.34.5.1275-1276.1996. J Clin Microbiol. 1996. PMID: 8727917 Free PMC article. Review.
-
[Diphtheroids and nontoxigenic Corynebacterium diphtheriae in the etiology of diphtheria].Mikrobiol Z. 1999 Jul-Aug;61(4):81-9. Mikrobiol Z. 1999. PMID: 10565154 Review. Russian.
Cited by
-
Seroprevalence of Diphtheria in Antananarivo, Madagascar, and Cambodia.Open Forum Infect Dis. 2025 Feb 20;12(3):ofaf091. doi: 10.1093/ofid/ofaf091. eCollection 2025 Mar. Open Forum Infect Dis. 2025. PMID: 40066087 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical