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Comment
. 2022 Sep;32(9):799-800.
doi: 10.1038/s41422-022-00691-1.

Treatment for giant congenital nevi moves a step closer

Joanna Pozniak  1   2 , Jean-Christophe Marine  3   4
Affiliations
Comment

Treatment for giant congenital nevi moves a step closer

Joanna Pozniak et al. Cell Res. 2022 Sep.
No abstract available

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Figures

Fig. 1
Fig. 1. Modeling and targeting giant congenital nevi in mice.
a Representation of the Tyr-CreERT2 Nras, Dct-Cre Nras, and xenograft mouse models that recapitulate the giant congenital nevi. b Treatment of the adult and neonatal Dct-Cre Nras mice and the GCMN xenografts in an adult mouse with SADBE significantly diminishes pigmentation. Created with BioRender.com.
See this image and copyright information in PMC

Comment on

  • Topical therapy for regression and melanoma prevention of congenital giant nevi.
    Choi YS, Erlich TH, von Franque M, Rachmin I, Flesher JL, Schiferle EB, Zhang Y, Pereira da Silva M, Jiang A, Dobry AS, Su M, Germana S, Lacher S, Freund O, Feder E, Cortez JL, Ryu S, Babila Propp T, Samuels YL, Zakka LR, Azin M, Burd CE, Sharpless NE, Liu XS, Meyer C, Austen WG Jr, Bojovic B, Cetrulo CL Jr, Mihm MC, Hoon DS, Demehri S, Hawryluk EB, Fisher DE. Choi YS, et al. Cell. 2022 Jun 9;185(12):2071-2085.e12. doi: 10.1016/j.cell.2022.04.025. Epub 2022 May 12. Cell. 2022. PMID: 35561684 Free PMC article.

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Supplementary concepts