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. 2022 Jun 28:2022:5169892.
doi: 10.1155/2022/5169892. eCollection 2022.

Effect of Kvass on Improving Functional Dyspepsia in Rats

Zhanmei Shao  1   2 , Jidong Zhong  2 , Yuming Fang  2 , Yongqiang Ma  3
Affiliations

Effect of Kvass on Improving Functional Dyspepsia in Rats

Zhanmei Shao et al. Comput Math Methods Med. .

Abstract

Functional dyspepsia (FD) is a common digestive system disease, and probiotics in the treatment of FD have a good curative effect. Patients with gastrointestinal diseases often show a poor response to traditional drug treatments and suffer from adverse reactions. Kvass can be used as a functional drink without side effects to improve the symptoms of FD patients. The results showed that compared with those of the model group, the body weight and food intake of the treatment group were significantly increased (P < 0.05), and the gastric residual rate of the treatment group was significantly decreased (P < 0.05); the amount of pepsin in the treatment group was significantly higher than that in the model group (P < 0.05); a high dose of Kvass could increase the contents of ghrelin, motilin (MTL), and gastrin (GAS) in the plasma and decrease the contents of vasoactive intestinal peptide (VIP) in the plasma; the contents of ghrelin, MTL, and GAS in the gastric antrum were also increased in the high-dose group. Kvass beverage can significantly improve the gastrointestinal function of rats, which may be because it can improve the contents of ghrelin, MTL, GAS, and VIP in both the serum and gastric antrum by regulating the expression of short-chain fatty acids in the colon.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Results of body weight and feed intake in rats ((a) feed intake; (b) body weight). ∗Compared with the normal group, the difference was significant (P < 0.05). ∗∗Significantly different from that of the normal group (P < 0.01). #Compared with the model group, the difference was significant (P < 0.05).
Figure 2
Figure 2
Effect of Kvass on the contents of ghrelin, MTL, GAS, and VIP in rats ((a) effects of Kvass on the contents of ghrelin, MTL, GAS, and VIP in the rat plasma; (b) effects of Kvass on the contents of ghrelin, MTL, GAS, and VIP in the rat gastric antrum).
Figure 3
Figure 3
Detection of gastric residual rate and intestinal propulsion rate in rats.
See this image and copyright information in PMC

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