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Case Reports
. 2022 Jun 27:38:101693.
doi: 10.1016/j.rmcr.2022.101693. eCollection 2022.

Unusual presentation of a small cell lung cancer with bilateral breast metastases: Case report and a brief review of the literature

Mark Bannon  1 , Creticus Marak  2 , Adrita Ashraf  1 , Chelsea Smith  1 , Matthew Nunley  1 , Achuta Kumar Guddati  3 , Prashant Kaushik  4
Affiliations
Case Reports

Unusual presentation of a small cell lung cancer with bilateral breast metastases: Case report and a brief review of the literature

Mark Bannon et al. Respir Med Case Rep. .

Abstract

Small cell lung cancer (SCLC) is a smoker's disease and occurs almost exclusively in smokers. SCLC is a high-grade neuroendocrine tumor and commonly presents as a central tumor with bulky mediastinal adenopathy. It is notorious for causing widespread disease and paraneoplastic syndromes. The usual sites of metastasis include the liver, brain, bone, and adrenals. SCLC presenting with breast metastasis is unusual; however, there are reports of unilateral and bilateral breast metastases. SCLC with bilateral breast metastases is extremely rare, with only five previously reported cases available in the literature. We are taking this opportunity to report and add to the growing literature on the unusual presentation of a small cell lung cancer with bilateral breast metastases.

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Conflict of interest statement

We have no conflicts to declare.

Figures

Fig. 1
Fig. 1
Ultrasound bilateral breasts.
Fig. 2
Fig. 2
Mammography of bilateral breasts.
Fig. 3
Fig. 3
CT chest revealing left hilar mass and bilateral breast masses.
Image 1
Image 1
A: H&E showing the characteristic small to ovel and short spindle-shaped cells arranged in sheets, without distinct nuclei representative of small cell lung cancer.
See this image and copyright information in PMC

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