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Case Reports
. 2022 May 26;10(15):5036-5041.
doi: 10.12998/wjcc.v10.i15.5036.

Metastasis of liver cancer to the thyroid after surgery: A case report

Hao-Chen Zhong  1 , Zhao-Wei Sun  1 , Guang-Hua Cao  2 , Wei Zhao  3 , Kai Ma  3 , Bing-Yuan Zhang  3 , Yu-Jie Feng  4
Affiliations
Case Reports

Metastasis of liver cancer to the thyroid after surgery: A case report

Hao-Chen Zhong et al. World J Clin Cases. .

Abstract

Background: Secondary thyroid malignancies are rarely reported, especially thyroid metastasis after resection of hepatocellular carcinoma (HCC). We report a patient with thyroid metastasis after resection of HCC.

Case summary: A 42-year-old female underwent partial hepatectomy for HCC three years ago. She attended hospital because of neck discomfort. After various examinations, she was diagnosed with metastatic HCC. She survived after surgical resection of the affected side of the thyroid.

Conclusion: Although secondary malignant tumor of the thyroid is classified as distant metastasis, surgical resection is still necessary according to the patient's condition.

Keywords: Case report; Hepatocellular carcinoma; Liver cancer; Metastasis; Surgery; Thyroid gland.

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Conflict of interest statement

Conflict-of-interest statement: No conflict of interest.

Figures

Figure 1
Figure 1
Thyroid color Doppler ultrasound showed hypoechoic nodules in the left lobe of the thyroid (TI-RADS 4b).
Figure 2
Figure 2
Tumor infiltration seen in the thyroid tissue.
Figure 3
Figure 3
Pathology showed liver cancer infiltration in thyroid tissue. A: H&E, × 100; B: H&E, × 200.
Figure 4
Figure 4
Immunohistochemical examination was positive for hepatocytes (× 100) and arginase-1 (× 100), and negative for TTF-1 (× 100). A: Hepatocytes (× 100); B: Arginase-1 (× 100); C: TTF-1 (× 100).
See this image and copyright information in PMC

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