Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Sep 29;11(9):413-416.
doi: 10.1093/jpids/piac046.

Inactivated Poliovirus Vaccine Closing the Type 2 Immunity Gap in Vietnam

Dang Thi Thanh Huyen  1 , Dang Duc Anh  1 , Nguyen Thanh Trung  1 , Duong Thi Hong  1 , Tran Trung Thanh  1 , Luong Ngoc Truong  2 , Visalakshi Jeyaseelan  3 , Rocio Lopez Cavestany  3 , William S Hendley  4 , Bernardo A Mainou  5 , Ondrej Mach  3
Affiliations

Inactivated Poliovirus Vaccine Closing the Type 2 Immunity Gap in Vietnam

Dang Thi Thanh Huyen et al. J Pediatric Infect Dis Soc. .

Abstract

This was a cross-sectional community-based serological survey of polio antibodies assessing the immunogenicity of inactivated poliovirus vaccine (IPV) focusing on poliovirus serotype 2. IPV was administered to 5-month-old children. Type 2 antibody seroprevalence when measured 1 month after IPV administration was >95%. One IPV dose successfully closed the immunity gap.

Keywords: Vietnam; inactivated poliovirus vaccine; polio eradication; poliomyelitis; routine immunization.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Seroprevalences of types 1, 2, and 3 by age groups (group 1: 5-11 months; group 2: 12-15 months). Samples were collected 1 month after IPV administration in group 1, and 7-10 months after IPV administration in group 2. IPV, inactivated poliovirus vaccine.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. WHO, GPEI. Global Wild Poliovirus 2016-2021 GPEI2021 [updated November 30, 2021]. https://polioeradication.org/wp-content/uploads/2021/12/weekly-polio-ana.... Accessed May 10, 2022.
    1. GPEI. Fact sheet: vaccine-derived poliovirus. In: World Health Organization, ed. 2019. https://polioeradication.org/wp-content/uploads/2018/07/GPEI-cVDPV-Fact-.... Accessed May 10, 2022.
    1. GPEI. Polio Eradication & Endgame Strategic Plan 2013-2018. In: World Health Organization, ed. WHO Press, Geneva, Switzerland; 2013:51–72. https://polioeradication.org/wp-content/uploads/2016/07/PEESP_EN_A4.pdf. Accessed May 10, 2022.
    1. GPEI. Polio Eradication & Endgame Strategic Plan 2019-2023. In: World Health Organization, ed. World Health Organization on behalf of the Global Polio Eradication Initiative,Switzerland; 2019: 28–33. https://polioeradication.org/wp-content/uploads/2019/06/english-polio-en.... Accessed May 10, 2022.
    1. GPEI. Planning for IPV introduction FAQs. In: World Health Organization, editor. 2014. https://www.paho.org/hq/dmdocuments/2014/IPV-IntroductionFAQ-e.pdf. Accessed May 10, 2022.

Substances