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. 2022 Sep 29;11(9):413-416.
doi: 10.1093/jpids/piac046.

Inactivated Poliovirus Vaccine Closing the Type 2 Immunity Gap in Vietnam

Dang Thi Thanh Huyen  1 , Dang Duc Anh  1 , Nguyen Thanh Trung  1 , Duong Thi Hong  1 , Tran Trung Thanh  1 , Luong Ngoc Truong  2 , Visalakshi Jeyaseelan  3 , Rocio Lopez Cavestany  3 , William S Hendley  4 , Bernardo A Mainou  5 , Ondrej Mach  3
Affiliations

Inactivated Poliovirus Vaccine Closing the Type 2 Immunity Gap in Vietnam

Dang Thi Thanh Huyen et al. J Pediatric Infect Dis Soc. .

Abstract

This was a cross-sectional community-based serological survey of polio antibodies assessing the immunogenicity of inactivated poliovirus vaccine (IPV) focusing on poliovirus serotype 2. IPV was administered to 5-month-old children. Type 2 antibody seroprevalence when measured 1 month after IPV administration was >95%. One IPV dose successfully closed the immunity gap.

Keywords: Vietnam; inactivated poliovirus vaccine; polio eradication; poliomyelitis; routine immunization.

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Figures

Figure 1.
Figure 1.
Seroprevalences of types 1, 2, and 3 by age groups (group 1: 5-11 months; group 2: 12-15 months). Samples were collected 1 month after IPV administration in group 1, and 7-10 months after IPV administration in group 2. IPV, inactivated poliovirus vaccine.
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