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. 2022 Oct;58(5):666-674.
doi: 10.23736/S1973-9087.22.07510-4. Epub 2022 Jul 8.

Predictors of functional outcomes in adults with brain tumor undergoing rehabilitation treatment: a systematic review

Anna Pieczyńska  1   2 , Agnieszka Pilarska  3 , Katarzyna Hojan  4   3
Affiliations

Predictors of functional outcomes in adults with brain tumor undergoing rehabilitation treatment: a systematic review

Anna Pieczyńska et al. Eur J Phys Rehabil Med. 2022 Oct.

Abstract

Introduction: The number of diagnosed brain tumors (BT) has increased in recent years. The results of treatment of patients with surgery, chemotherapy and radiotherapy are also improving and their survival rate has increased significantly. Symptoms of the disease and side effects of oncological treatment may reduce the functional performance of patients. It is so important to conduct rehabilitation in this group of patients. The aim of this systematic review is to identify predictors of effective rehabilitation in aspects of physical functioning of BT patients. The study was registered with health and social care, welfare, public health, education, crime, justice and international development departments, where there is a health-related interest outcome PROSPERO. We have received registration number is: CRD42021269398.

Evidence acquisition: To find relevant publications, the algorithm of keywords ("brain tumor") AND (rehabilitation OR "physical activity" OR exercise OR "physical therapy") was used. The search was conducted in PubMed, Web of Science, PEDro, ClinicalTrials.gov and Cochrane Library. Information was extracted using the PICO format (i.e., participants, intervention, comparison, outcomes).

Evidence synthesis: the initial search identified a total of 1122 results, and 21 articles met the criteria and were selected for analysis.

Conclusions: The results present that rehabilitation is an important and safe cancer encouraging therapy, brings functional benefits. The type of rehabilitation program, especially in BT patients, depends on many factors such as time and type of oncological treatment, general conditions which is strongly related to the general functioning of the patient. It still is a need for clinical research into the safety and effectiveness of rehabilitation interventions already during radio or chemotherapy in this group of cancer patients.

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Conflict of interest statement

Conflicts of interest.—The authors certify that there is no conflict of interest with any financial organization regarding the material discussed in the manuscript.

Figures

Figure 1
Figure 1
—PRISMA flow diagram of the search strategy process.
Figure 2
Figure 2
—Detailed assessment of individual sections expressed as a percentage.
See this image and copyright information in PMC

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