A review on artificial pancreas and regenerative medicine used in the management of Type 1 diabetes mellitus

Abstract

Diabetes mellitus is one of the fastest-growing lifestyle disorders in the world. While numerous regimes have been developed to manage diabetes, there continue to be high numbers of diabetes-related deaths worldwide. The review gives a brief introduction to the pathology and aetiology of the disorder, different solutions developed over time with their advantages and disadvantages, and highlights the technological components and challenges of the latest technologies: artificial pancreas and regenerative medicine. The study is restricted to a set of high-quality publications from the last decade.

Keywords: Diabetes; artificial pancreas; bionic pancreas; continuous glucose monitoring; diabetes management; glucose sensor; insulin delivery; regenerative tissue.