Comment
doi: 10.1016/j.molcel.2022.06.017.
What's NEXT for the exosome?
Affiliations
- PMID: 35803215
- DOI: 10.1016/j.molcel.2022.06.017
Item in Clipboard
Comment
What's NEXT for the exosome?
Mol Cell.
.
Free article
Abstract
Two recent studies by Gerlach et al. (2022) and Puno and Lima (2022) provide new structural and functional insight into the assembly of the nuclear exosome targeting complex (NEXT) and how it may target specific classes of RNA for degradation.
Copyright © 2022 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
-
Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.Cell. 2022 Jun 9;185(12):2132-2147.e26. doi: 10.1016/j.cell.2022.04.016. Cell. 2022. PMID: 35688134 Free PMC article.
-
Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.Mol Cell. 2022 Jul 7;82(13):2505-2518.e7. doi: 10.1016/j.molcel.2022.04.011. Epub 2022 Jun 9. Mol Cell. 2022. PMID: 35688157 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
