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. 1987 Jan-Feb;8(1):87-97.
doi: 10.1002/bdd.2510080110.

Definition of mean residence times in pharmacokinetics

D J Cutler

Definition of mean residence times in pharmacokinetics

D J Cutler. Biopharm Drug Dispos. 1987 Jan-Feb.

Abstract

A new definition of the mean residence time is proposed which includes the commonly used definition as a special case. The advantage of the new definition is that it applies for both linear and non-linear systems. Some practical advantages which follow from the new definition are discussed. Procedures for using urinary excretion data in mean residence time estimation are discussed.

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