Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jun 28;19(13):7923.
doi: 10.3390/ijerph19137923.

Effects of a Long-Term Monitored Exercise Program on Aerobic Fitness in a Small Group of Children with Cystic Fibrosis

Wolfgang Gruber  1   2 , Florian Stehling  1 , Christopher Blosch  1 , Stefanie Dillenhoefer  3 , Margarete Olivier  1 , Cordula Koerner-Rettberg  4 , Sivagurunathan Sutharsan  5 , Uwe Mellies  1 , Christian Taube  5 , Matthias Welsner  5
Affiliations

Effects of a Long-Term Monitored Exercise Program on Aerobic Fitness in a Small Group of Children with Cystic Fibrosis

Wolfgang Gruber et al. Int J Environ Res Public Health. .

Abstract

Background: The aim of this study was to investigate the effects of a monitored exercise program on aerobic fitness in children with cystic fibrosis (CF). Methods: Six children (2f/4m) with ages ranging from 6 to 14 years (11.3 ± 3.3 years.) and a mean ppFEV1 102.5 ± 13.5% pred. participated in the partially monitored 12-month exercise program. VO2peak and Wpeak were used as parameters of aerobic fitness. Incremental Cardio-Pulmonary Exercise Tests (CPETs) were performed before the program began (T1), after 6 months (T3) of monitoring, and after a further 6 months (T4) without monitoring. Habitual physical activity (HPA) was assessed with accelerometry. Results: The values of VO2peak and Wpeak improved slightly from T1 to T3 (p > 0.05), without a further increase after monitoring was stopped (T4). However, the VO2peak and Wpeak values were higher after monitoring was stopped compared to at T1. The exercise program with and without monitoring (p > 0.05) had no or only a slight effect on the FEV1 values, steps/day, and the intensity of HPA. Conclusions: Monitoring seems to facilitate the achievement of beneficial effects on physical fitness in CF children. For that reason, continuous individual exercise monitoring programs that involve close contact with an exercise therapist should be provided to maintain long-term motivation and participation in physical activities and sport activities during leisure time.

Keywords: VO2peak; aerobic fitness; children; cystic fibrosis; long-term exercise program; physical activity.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Selection flowchart of participants.
Figure 2
Figure 2
Timeline of CFmobile exercise program.
Figure 3
Figure 3
Increase in CPET parameters in percent over the course of the 12months partially monitored exercise program.
Figure 4
Figure 4
In crease of VO2peak over the course of the 12months partially monitored exercise program.
See this image and copyright information in PMC

References

    1. Bell S.C., Mall M.A., Gutierrez H., Macek M., Madge S., Davies J.C., Burgel P.R., Tullis E., Castaños C., Castellani C., et al. The future of cystic fibrosis care: A global perspective. Lancet. Respir. Med. 2020;8:65–124. doi: 10.1016/S2213-2600(19)30337-6. - DOI - PMC - PubMed
    1. Elborn J.S. Cystic fibrosis. Lancet (Lond. Engl.) 2016;388:2519–2531. doi: 10.1016/S0140-6736(16)00576-6. - DOI - PubMed
    1. Jackson A.D., Daly L., Jackson A.L., Kelleher C., Marshall B.C., Quinton H.B., Fletcher G., Harrington M., Zhou S., McKone E.F., et al. Validation and use of a parametric model for projecting cystic fibrosis survivorship beyond observed data: A birth cohort analysis. Thorax. 2011;66:674–679. doi: 10.1136/thoraxjnl-2011-200038. - DOI - PMC - PubMed
    1. Castellani C., Duff A.J.A., Bell S.C., Heijerman H.G.M., Munck A., Ratjen F., Sermet-Gaudelus I., Southern K.W., Barben J., Flume P.A., et al. ECFS best practice guidelines: The 2018 revision. J. Cyst. Fibros. Off. J. Eur. Cyst. Fibros. Soc. 2018;17:153–178. doi: 10.1016/j.jcf.2018.02.006. - DOI - PubMed
    1. Radtke T., Nevitt S.J., Hebestreit H., Kriemler S. Physical exercise training for cystic fibrosis. Cochrane Database Syst. Rev. 2017;11 doi: 10.1002/14651858.CD002768.pub4. - DOI - PMC - PubMed