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. 2022 Jun 28;11(13):3733.
doi: 10.3390/jcm11133733.

Quality of Life after Surgical Treatment of Brain Tumors

Agnieszka Królikowska  1 , Karolina Filipska-Blejder  1 , Renata Jabłońska  1 , Beata Haor  1 , Anna Antczak-Komoterska  2 , Monika Biercewicz  3 , Lech Grzelak  4 , Marek Harat  5 , Robert Ślusarz  1
Affiliations

Quality of Life after Surgical Treatment of Brain Tumors

Agnieszka Królikowska et al. J Clin Med. .

Abstract

Quality of life is one of the parameters that characterize the success of brain tumor treatments, along with overall survival and a disease-free life. Thus, the main aim of this research was to evaluate the quality of life after the surgical treatment of brain tumors. The research material included 236 patients who were to undergo surgery for brain tumors. The participants completed the quality of life questionnaires EORTC QLQ-C30 (version 3.0) and EORTC QLQ-BN20 on the day of admission to the department, on the fifth day after the removal of the brain tumor, and thirty days after the surgical procedure. Descriptive statistics, Student's t-test, the Kruskal-Wallis test, the Shapiro-Wolf test, ANOVA, and Fisher's least significant difference post hoc test were performed. The mean score of the questionnaire before the surgical procedure amounted to 0.706, 5 days after surgery it amounted to 0.614, and 30 days after surgery to 0.707. The greatest reduction in the quality of life immediately after the procedure was observed in patients with low-grade glial tumors (WHO I, II) and extracerebral tumors (meningiomas and neuromas). Thirty days after surgery, an improvement in the quality of life was observed in all included groups. The greatest improvement was recorded in the group of patients operated on for meningioma and neuroblastoma, and the lowest in patients treated for metastatic tumors. Contemporary surgical procedures used in neurosurgery reduce the quality of life in patients with brain tumors only in the early postoperative period. Histopathological diagnoses of these tumors impact the quality of life of patients.

Keywords: brain tumor; quality of life; surgery.

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Conflict of interest statement

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

Figures

Figure 1
Figure 1
Recruitment flow chart.
Figure 2
Figure 2
The influence of time and histopathological diagnosis on the quality of life in people with brain tumors.
Figure 3
Figure 3
Influence of individual symptoms on quality of life in different time measures.
See this image and copyright information in PMC

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