Multi-day perfusion of transplant organs: The how and the why
- PMID: 35809558
- DOI: 10.1016/j.medj.2022.06.008
Multi-day perfusion of transplant organs: The how and the why
Abstract
In a recent paper, Clavien et al. demonstrate the successful transplant of a sub-optimal donor liver using multi-day normothermic machine perfusion. This technological milestone opens up exciting new avenues for liver transplantation with the potential to ameliorate donor organ shortages and permit targeted therapeutic interventions.
Copyright © 2022 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests P.F. is a co-founder, Chief Medical Officer (part-time), and stockholder of OrganOx, an Oxford University spinout company that was established to develop clinical normothermic machine perfusion technology. He is an inventor named on the patent that supports the underlying perfusion technology. A.S. has no competing interests to declare.
Comment on
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Transplantation of a human liver following 3 days of ex situ normothermic preservation.Nat Biotechnol. 2022 Nov;40(11):1610-1616. doi: 10.1038/s41587-022-01354-7. Epub 2022 May 31. Nat Biotechnol. 2022. PMID: 35641829
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