Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Oct-Dec;88(4):341-346.
doi: 10.1016/j.rgmxen.2022.06.012. Epub 2022 Jul 7.

Prevalence and characteristics of gastroesophageal reflux disease in pregnant women

Y-L T Le  1 , M N Luu  2 , L H Mai  3 , A T Hoang  3 , T T Nguyen  3 , D T Quach  4
Affiliations
Free article

Prevalence and characteristics of gastroesophageal reflux disease in pregnant women

Y-L T Le et al. Rev Gastroenterol Mex (Engl Ed). 2023 Oct-Dec.
Free article

Abstract

Introduction and aims: The prevalence of gastroesophageal reflux disease (GERD) has been reported to be increasing in recent years. However, there have been few reports on the prevalence of GERD during pregnancy in the Asian population. The aim of our study was to evaluate the prevalence and characteristics of GERD in Vietnamese pregnant women.

Materials and methods: This cross-sectional study was conducted at the antenatal clinic of the Nhan Dan Gia Dinh Hospital, Ho Chi Minh, Vietnam. Four hundred females, at various stages of pregnancy, were enrolled. GERD was diagnosed if there was troublesome heartburn and/or acid regurgitation, at least once a week, during the current pregnancy.

Results: The overall prevalence of GERD in pregnancy was 38.5% (154/400). The prevalence of GERD in the third trimester was significantly higher than that in the second trimester (46.8% vs. 30.7%, P=0.008) and tended to be higher than its prevalence in the first trimester (46.8% vs. 35.4%, P=0.051). In the pregnant women with GERD, the frequency of regurgitation was significantly higher than that of heartburn (92.9% vs. 30.5%, P<0.001). Those typical symptoms were more prevalent in the daytime, compared with nighttime.

Conclusion: Our study showed that GERD was prevalent during pregnancy in Vietnam. In the pregnant women with GERD, regurgitation was much more common than heartburn, and those typical reflux symptoms occurred more frequently in the daytime, compared with nighttime.

Keywords: Embarazo; Gastroesophageal reflux; Heartburn; Pirosis; Pregnancy; Reflujo gastroesofágico; Vietnam.

PubMed Disclaimer

LinkOut - more resources