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Case Reports
. 2022 Jul 4:44:102151.
doi: 10.1016/j.eucr.2022.102151. eCollection 2022 Sep.

Extraskeletal myxoid chondrosarcoma of the penis: Description of a rare tumor arising in an unusual location

Khaled A Murshed  1 , Bashar Aldaraiseh  1 , Aalaa Kambal  2 , Alaaldin Badawi  3 , Issam Albozom  1
Affiliations
Case Reports

Extraskeletal myxoid chondrosarcoma of the penis: Description of a rare tumor arising in an unusual location

Khaled A Murshed et al. Urol Case Rep. .

Abstract

Extraskeletal myxoid chondrosarcoma (EMC) is a rare malignant soft tissue tumor that most commonly arises in the extremities. Its occurrence in the genitourinary tract is extremely uncommon. We present an 82-year-old man who was found to have incidental pulmonary metastasis by imaging studies. The biopsy findings from the lung were in favor of metastatic EMC. The primary mass was found to be located at the penile root, which was confirmed to be EMC. This case adds to the few reported cases of EMC arising in the perineal region, and sheds light on the clinical behavior of this soft tissue tumor.

Keywords: Extraskeletal myxoid chondrosarcoma; Lung; Metastasis; Penis; Perineum.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Computed Tomography scan of the thorax. A, coronal and B, axial planes showing multiple variable-sized solid pulmonary nodules (black arrows) at both lung parenchyma, in keeping with metastasis.
Fig. 2
Fig. 2
Microscopic and immunohistochemical features of the tumor. A and B, the tumor cells are arranged in cords and trabeculae that are embedded in myxoid matrix (Hematoxylin & eosin stain x200). C, High power view shows uniform oval to spindle tumor cells that have uniform chromatin and eosinophilic cytoplasm (Hematoxylin & eosin stain x400). D, the tumor cells show focal nuclear and cytoplasmic staining for S100 protein (Immunohistochemistry x200).
Fig. 3
Fig. 3
Magnetic Resonance Imaging of the pelvis. A, Sagittal T2 weighted and B, axial T2 weighted MR images showing diffuse infiltrative T2 bright signal intensity lesion along the whole penile shaft (yellow star) extending into superficial extra-albugineal tissue (white bold arrows) and involving the left inferior pubic ramus (yellow arrowhead). In addition, multiple lobulated T2 bright signal intensity lesions inferior to the penile root (curved white arrows). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
See this image and copyright information in PMC

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