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. 2022 Jun 6;10(16):5266-5274.
doi: 10.12998/wjcc.v10.i16.5266.

Long-term outcomes of high-risk percutaneous coronary interventions under extracorporeal membrane oxygenation support: An observational study

Yi-Xiong Huang  1 , Zheng-Ming Xu  2 , Li Zhao  2 , Yi Cao  2 , Yu Chen  2 , Yi-Gang Qiu  2 , Ying-Ming Liu  2 , Peng-Yu Zhang  2 , Jiang-Chun He  2 , Tian-Chang Li  3
Affiliations

Long-term outcomes of high-risk percutaneous coronary interventions under extracorporeal membrane oxygenation support: An observational study

Yi-Xiong Huang et al. World J Clin Cases. .

Abstract

Background: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) offers hemodynamic support for patients undergoing high-risk percutaneous coronary interventions (PCIs). However, long-term outcomes associated with VA-ECMO have not previously been studied.

Aim: To explore long-term outcomes in high-risk cases undergoing PCI supported by VA-ECMO.

Methods: In the present observational cohort study, 61 patients who received VA-ECMO-supported high-risk PCI between April 2012 and January 2020 at the Sixth Medical Center of Chinese People's Liberation Army General Hospital were enrolled. The endpoint characteristics such as all-cause mortality, repeated cardiovascular diseases, and cardiac death were examined.

Results: Among 61 patients, three failed stent implantation due to chronic total occlusions with severely calcified lesions. One patient showed VA-ECMO intolerance because of high left ventricular afterload. PCI was successfully performed in 57 patients (93.4%). The in-hospital mortality was 23.0%, and the overall survival was 45.9%, with a median follow-up period of 38.6 (8.6-62.1) mo.

Conclusion: VA-ECMO can be used as a support in patients undergoing high-risk PCI as it is associated with favorable long-term patient survival.

Keywords: High-risk percutaneous coronary intervention; Long-term survival; Overall survival; Venoarterial extracorporeal membrane oxygenation.

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Conflict of interest statement

Conflict-of-interest statement: There are no conflicts of interest to report.

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