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. 2022 Jun 22:9:931137.
doi: 10.3389/fvets.2022.931137. eCollection 2022.

Comparative Mitochondrial Genomic Analysis Robustly Supported That Cat Tapeworm Hydatigera taeniaeformis (Platyhelminthes: Cestoda) Represents a Species Complex

Hui-Mei Wang  1 , Rong Li  1 , Yuan-Ping Deng  1 , Guo-Hua Liu  1 , Yi-Tian Fu  1
Affiliations

Comparative Mitochondrial Genomic Analysis Robustly Supported That Cat Tapeworm Hydatigera taeniaeformis (Platyhelminthes: Cestoda) Represents a Species Complex

Hui-Mei Wang et al. Front Vet Sci. .

Abstract

Hydatigera taeniaeformis is one of the most common intestinal tapeworms that has a worldwide distribution. In this study, we sequenced the complete mitochondrial (mt) genome of H. taeniaeformis from the leopard cat (designated HTLC) and compared it with those of H. taeniaeformis from the cat in China (designated HTCC) and Germany (designated HTCG). The complete mt genome sequence of HTLC is 13,814 bp in size, which is 167 bp longer than that of HTCC and is 74 bp longer than that of HTCG. Across the entire mt genome (except for the two non-coding regions), the sequence difference was 3.3% between HTLC and HTCC, 12.0% between HTLC and HTCG, and 12.1% between HTCC and HTCG. The difference across both nucleotide and amino acid sequences of the 12 protein-coding genes was 4.1 and 2.3% between the HTLC and HTCC, 13.3 and 10.0% between the HTLC and HTCG, and 13.8 and 10.6% between the HTCC and HTCG, respectively. Phylogenetic analysis based on concatenated amino acid sequences of 12 protein-coding genes showed the separation of H. taeniaeformis from different hosts and geographical regions into two distinct clades. Our analysis showed that the cat tapeworm H. taeniaeformis represents a species complex. The novel mt genomic datasets provide useful markers for further studies of the taxonomy and systematics of cat tapeworm H. taeniaeformis.

Keywords: Hydatigera taeniaeformis; cat tapeworm; comparative analaysis; mitochondrial genome; species complex.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
The organization of mitochondrial genome of Hydatigera taeniaeformis China isolate. Gene scaling is only approximate. “NCR1” refers to a short non-coding region and “NCR2” refers to a long non-coding region.
Figure 2
Figure 2
Inferred phylogenetic relationship among species from the family Taeniidae. The concatenated amino acid sequences of 12 mitochondrial protein-coding genes were analyzed utilizing Maximum likelihood (ML) and Bayesian analysis (BI), using Paruterina candelabraria as an outgroup. Hydatigera taeniaeformis in the red font is China isolate from the leopard cat in the present study.
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