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. 2022 Jun 30:2022:6213716.
doi: 10.1155/2022/6213716. eCollection 2022.

Enteral Nutrition: Based on the Combination of Nutrison Fibre and TPF-DM with A Marine Biological-Based Active Polysaccharide Preparation

Qiuyue Tang  1 , Yaqin Cheng  1
Affiliations

Enteral Nutrition: Based on the Combination of Nutrison Fibre and TPF-DM with A Marine Biological-Based Active Polysaccharide Preparation

Qiuyue Tang et al. Comput Math Methods Med. .

Abstract

Good nutrition is essential for human growth, wound healing, and spiritual vitality. However, some individuals are unable to eat or experience gastrointestinal problems such as severe diarrhea, vomiting, gastric retention, and even gastrointestinal bleeding for a variety of causes. Therefore, it has important clinical significance to provide patients with required nutrients and maintain the integrity of the body's tissues and organs through enteral nutrition. Based on this, this work uses a dual carrier of polylactic acid (PLA) and polyvinyl alcohol (PVA) to carry marine biopolysaccharides combined with sodium alginate (PSS) and successfully obtains the intestinal tract based on marine bioactive polysaccharides. Nutritional oral biological preparations (PSS-PLA/PVA) also cooperate with enteral nutritional suspension (diabetes) (TPF-DM) and Nutrison fibre to provide enteral nutritional support for critically ill patients. PSS-PLA/PVA has been shown in clinical studies to increase the effect of enteral nutrition support, the function of intestinal T lymphatic tissue, and the ability to control immunological function, indicating that it is worthy of further clinical development.

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Conflict of interest statement

The authors declared that they have no conflicts of interest regarding this work.

Figures

Figure 1
Figure 1
Enteral nutrition administration and absorption route.
Figure 2
Figure 2
Characterization of a novel oral preparation of marine biologically active polysaccharide-sodium alginate-polylactic acid/polyvinyl alcohol (PSS-PLA/PVA): (a) electron microscopy characterization diagram; (b) graph of particle size distribution.
Figure 3
Figure 3
Analysis of the cumulative release rate of polysaccharide-sodium alginate-polylactic acid/polyvinyl alcohol (PSS-PLA/PVA) in artificial gastric juice and artificial intestinal juice.
Figure 4
Figure 4
The effect of enteral nutrition on nutritional evaluation indexes of patients with different degrees of risk: (a) the effect on albumin (ALB) content; (b) the effect on hemoglobin (HB) content; (c) the effect on prealbumin (pre-ALB) content. ∗P < 0.05.
Figure 5
Figure 5
The effect of enteral nutrition on the total number of T cells (TLC) in patients with different degrees of risk.
Figure 6
Figure 6
The effect of enteral nutrition on the immune function of patients with different degrees of risk: (a) the effect on immunoglobulin A content; (b) the effect on immunoglobulin G content; (c) the effect on immunoglobulin M content.
Figure 7
Figure 7
The effect of enteral nutrition on the incidence of gastrointestinal reactions in patients.
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