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. 2022 Jun 29:2022:4977922.
doi: 10.1155/2022/4977922. eCollection 2022.

The Effect of Different Nutritional Nursing Support on the Nutritional Status and Disease Recovery of Elderly Patients with Gastrointestinal Tumors during the Perioperative Period

Lingzhi Chen  1 , Sixin Zheng  1 , Qi Xie  1 , Liping Huang  1 , Guang Yin  1
Affiliations

The Effect of Different Nutritional Nursing Support on the Nutritional Status and Disease Recovery of Elderly Patients with Gastrointestinal Tumors during the Perioperative Period

Lingzhi Chen et al. Comput Math Methods Med. .

Abstract

Objective: This study explored the effect of different nutritional nursing support on nutritional status, immune function, postoperative bowel motility, and complications in elderly patients with gastrointestinal tumors during the perioperative period.

Methods: 300 patients with gastrointestinal tumors treated in the Department of Gastroenterology and anorectal surgery of Hangzhou First People's Hospital Affiliated with the Medical College of Zhejiang University from February 2018 to March 2020 were selected as the research objects in this study. Patients were divided into the early enteral nutrition (EEN) and total parenteral nutrition (TPN) groups (150 cases in each group) according to the principle of odd and even admission numbers. The patients in the EEN and TPN groups were given enteral nutrition nursing support and parenteral nutrition nursing support, respectively. The nutritional status, immune function, postoperative bowel motility, and complication rate of the two groups were evaluated 7 days after the operation.

Results: The nutritional indexes decreased 3 days after the operation and gradually recovered 7 days after the operation in both groups with different nutritional nursing support. The Hb, TRF, PAB, and ALB indexes in the TPN group were significantly lower than those in the EEN group (P < 0.01). On the 7th day after the operation, the indexes of peripheral blood immunoglobulin (IgG, IgM, and IgA) were significantly lower than those in the TPN group, and T lymphocyte subsets (CD4, CD8, and CD4/CD8) demonstrated that the immunological indexes of patients in the EEN group were significantly higher than those in the TPN group (P < 0.01). In terms of intestinal peristalsis, the time of first exhaust and first defecation in the EEN group was significantly shorter than that in the TPN group (P < 0.01) during the perioperative period. Furthermore, both groups had different degrees of complications, while patients demonstrated a lower complication rate in the EEN group compared to those in the TPN group, suggesting a safer postoperative mode. The results of subgroup analysis showed that the nutritional indexes of the gastric cancer group 7 days after operation were significantly higher than those of the colorectal cancer group under EEN and TPN nutritional support modes.

Conclusion: Clinical results have suggested that enteral nutrition nursing support can improve the perioperative nutritional status of elderly patients with gastrointestinal tumors by enhancing the immune function and promoting intestinal peristalsis. Meanwhile, the postoperative EEN mode reduces the rate of complications and demonstrates higher safety. Therefore, it has a high clinical application value.

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Conflict of interest statement

The authors declare that there are no conflicts of interest regarding the publication of this paper.

Figures

Figure 1
Figure 1
Flowchart of case grouping.
Figure 2
Figure 2
Nutritional indexes (Hb, TRF, PAB, and ALB) of the two groups. Hb of 3 and 7 days after the operation, TRF of 7 days after the operation, PAB of 7 days after the operation, and ALB of 7 days after the operation in the EEN group and the TPN group (P < 0.001); the rest of the differences were all P > 0.05.
Figure 3
Figure 3
Immune function indexes (IgG, IgM, IGA, CD4, CD8, and CD4/CD8) of the two groups. Before the operation, the difference between the EEN group and the TPN group was P > 0.05, and the difference between the two groups at 7 days after operation was P < 0.05.
Figure 4
Figure 4
Intestinal peristalsis indexes of the two groups. Compared with the EEN group ∗∗∗P < 0.001.
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