Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jun 18;15(6):857-867.
doi: 10.18240/ijo.2022.06.02. eCollection 2022.

Vitreous function and intervention of it with vitrectomy and other modalities

Yao Zong  1 , Qian-Ying Gao  2 , Yan-Nian Hui  3
Affiliations

Vitreous function and intervention of it with vitrectomy and other modalities

Yao Zong et al. Int J Ophthalmol. .

Abstract

The vitreous body, the largest intraocular component, plays a key role in eye development, refraction, cell barrier function, oxygen metabolism and the pathogenesis of assorted diseases. Age, refraction and systemic diseases can cause vitreous metabolic abnormalities. With the continuous development of vitrectomy techniques and equipment, vitreous injections and vitrectomies have increased over the recent decades. However, the normal oxygen tension gradient in the vitreous helps to protect the lens and anterior chamber angle from oxidative stress damage, whereas the increased vitreous oxygen tension around lens and the trabecular meshwork after vitrectomy. It may lead to postoperative nuclear cataract and increase the risk for glaucoma. As a conventional procedure, scleral buckling holds several advantages over vitrectomy in selected cases. This review raises concerns regarding the function of the vitreous and encourages conducting vitreous interventions prudently if it is possible.

Keywords: function; oxygen metabolism; scleral buckling; vitrectomy; vitreous.

PubMed Disclaimer

References

    1. Van de Put MAJ, Hooymans JMM, Los LI, Dutch Rhegmatogenous Retinal Detachment Study Group The incidence of rhegmatogenous retinal detachment in The Netherlands. Ophthalmology. 2013;120(3):616–622. - PubMed
    1. Li JQ, Welchowski T, Schmid M, Holz FG, Finger RP. Incidence of rhegmatogenous retinal detachment in Europe - A systematic review and Meta-analysis. Ophthalmologica. 2019;242(2):81–86. - PubMed
    1. Nielsen BR, Alberti M, Bjerrum SS, la Cour M. The incidence of rhegmatogenous retinal detachment is increasing. Acta Ophthalmol. 2020;98(6):603–606. - PubMed
    1. Li X, Beijing Rhegmatogenous Retinal Detachment Study Group Incidence and epidemiological characteristics of rhegmatogenous retinal detachment in Beijing, China. Ophthalmology. 2003;110(12):2413–2417. - PubMed
    1. Zou H, Zhang X, Xu X, Wang X, Liu K, Ho PC. Epidemiology survey of rhegmatogenous retinal detachment in Beixinjing District, Shanghai, China. Retina. 2002;22(3):294–299. - PubMed

LinkOut - more resources