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. 2022 Jun 18;15(6):924-931.
doi: 10.18240/ijo.2022.06.09. eCollection 2022.

The binocular intraocular lens power difference in eyes with different axial lengths

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The binocular intraocular lens power difference in eyes with different axial lengths

Ming-Hui Deng et al. Int J Ophthalmol. .

Abstract

Aim: To investigate the binocular intraocular lens (IOL) power difference in eyes with short, normal, and long axial lengths (AL) using Lenstar LS 900 optical biometry.

Methods: A total of 716 (1432 eyes) participants were included. The groups were categorized into short (group A: AL<22 mm), normal (group B: 22 mm≤AL≤25 mm), and long AL groups (group C: AL>25 mm). The central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), AL, anterior corneal keratometry, white-to-white (WTW), pupil diameter (PD), as well as IOL power calculated using embedded Barrett formula were assessed. Bland-Altman plots were used to test the agreement of the binocular parameters.

Results: In group A, the CCT of the right eye was significantly thinner than that of the left eye (P=0.044) with a difference of -2±8 µm [95% limits of agreement (LoA), -17.8 to 13.2 µm]. For group B, the PD and IOL power in the right eye were significantly lower than those of the left eye (P=0.001, <0.001) with a difference of -0.05±0.32 mm (95%LoA, -0.68 to 0.58 mm) and -0.18±1.01 D (95%LoA, -2.2 to 1.8 D). The AL of right eye was longer than that of the left eye (P=0.002) with a difference of 0.04±0.25 mm (95%LoA, -0.45 to 0.52 mm). No significant difference was observed for all the binocular parameters in group C. The percentage of participants with binocular IOL power difference within ±0.5 D were 62% (31/50), 68.3% (339/496), and 38.8% (66/170) in groups A, B, and C, respectively.

Conclusion: The binocular parameters related to IOL power are in good agreement, but the binocular IOL power difference of more than half of participants with long AL is more than 0.50 D.

Keywords: axial length; binocular difference; intraocular lens power.

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Figures

Figure 1
Figure 1. The Bland-Altman plots of the CCT, ACD, LT, AL, Kflat, Ksteep, WTW, PD, and IOL power between the right and left eyes in group A
The mean difference is demonstrated by the continuous line, whereas the 95% limits of agreement are indicated by the dashed lines. CCT: Central corneal thickness; ACD: Anterior chamber depth; LT: Lens thickness; AL: Axial length; Kflat: Flat keratometry; Ksteep: Steep keratometry; WTW: White-to-white distance; PD: Pupil diameter; IOL: Intraocular lens.
Figure 2
Figure 2. Scatterplots demonstrate the correlation between CCT, ACD, LT, AL, Kflat, Ksteep, WTW, PD, and IOL power for the binocular parameters in group A
The regression equation is demonstrated in the rectangular box (x represents right eye; y represents left eye). CCT: Central corneal thickness; ACD: Anterior chamber depth; LT: Lens thickness; AL: Axial length; Kflat: Flat keratometry; Ksteep: Steep keratometry; WTW: White-to-white distance; PD: Pupil diameter; IOL: Intraocular lens.
Figure 3
Figure 3. The Bland-Altman plots of CCT, ACD, LT, AL, Kflat, Ksteep, WTW, PD, and IOL power between right and left eyes in group B
The mean difference is demonstrated by the continuous line, whereas the 95% limits of agreement are indicated by the dashed lines. CCT: Central corneal thickness; ACD: Anterior chamber depth; LT: Lens thickness; AL: Axial length; Kflat: Flat keratometry; Ksteep: Steep keratometry; WTW: White-to-white distance; PD: Pupil diameter; IOL: Intraocular lens.
Figure 4
Figure 4. Scatterplots demonstrate the correlation between the CCT, ACD, LT, AL, Kflat, Ksteep, WTW, PD, and IOL power for the binocular parameters in group B
The regression equation is demonstrated in the rectangular box (x represents right eye; y represents left eye). CCT: Central corneal thickness; ACD: Anterior chamber depth; LT: Lens thickness; AL: Axial length; Kflat: Flat keratometry; Ksteep: Steep keratometry; WTW: White-to-white distance; PD: Pupil diameter; IOL: Intraocular lens.
Figure 5
Figure 5. Scatterplots demonstrate the correlation between the CCT, ACD, LT, AL, Kflat, Ksteep, WTW, PD, and IOL power for the binocular parameters in group C
The regression equation is demonstrated in the rectangular box (x represents right eye; y represents left eye). CCT: Central corneal thickness; ACD: Anterior chamber depth; LT: Lens thickness; AL: Axial length; Kflat: Flat keratometry; Ksteep: Steep keratometry; WTW: White-to-white distance; PD: Pupil diameter; IOL: Intraocular lens.
Figure 6
Figure 6. The Bland-Altman plots of CCT, ACD, LT, AL, Kflat, Ksteep, WTW, PD, and IOL power between right and left eyes in group C
The mean difference is demonstrated by the continuous line, whereas the 95% limits of agreement are indicated by the dashed lines. CCT: Central corneal thickness; ACD: Anterior chamber depth; LT: Lens thickness; AL: Axial length; Kflat: Flat keratometry; Ksteep: Steep keratometry; WTW: White-to-white distance; PD: Pupil diameter; IOL: Intraocular lens.
Figure 7
Figure 7. Number of participants of binocular intraocular lens power difference range (absolute value from 0 to 10 D) in groups A, B, and C
IOL: Intraocular lens; OD: Right eye; OS: Left eye.

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