Wide spread scars, hypertrophic scars, and keloids
- PMID: 3581659
Wide spread scars, hypertrophic scars, and keloids
Abstract
Patients with a wide scar may complain of having a "keloid," yet have a hypertrophic or a wide spread scar. The plastic surgeon should make the appropriate clinical diagnosis, because therapy varies depending on the condition present. A wide spread scar is best treated with excision and closure. A buried dermal flap may help to prevent recurrence, which is nevertheless likely to some degree. A hypertrophic scar can be distinguished from a keloid on clinical grounds. Although both may be red, nodular, and itchy, the keloid overgrows the original wound boundary and is much more likely to recur after surgical excision. Nonsurgical treatment of hypertrophic scars and keloids is similar, using repeated intralesional injections of Kenalog 40 mg per cc and sustained pressure on the lesion when possible. Surgical treatment differs for hypertrophic scars or keloids. Scar excision and closure, and selective Z-plasty, may be used in hypertrophic scars. In keloids, aggressive surgery is usually avoided, unless the lesion has a narrow pedicle. Surgery of keloids should be accompanied by intra- and postoperative Kenalog-40 injections, and on occasion by sustained pressure. Very large keloids may be resistant to medical management, and too aggressive for surgery owing to a high likelihood of recurrence. These difficult lesions serve as the impetus for continued biochemical and tissue culture research, seeking a biochemical means of control keloids.
Similar articles
-
[Modern treatment of keloids].Srp Arh Celok Lek. 1997 May-Jun;125(5-6):176-80. Srp Arh Celok Lek. 1997. PMID: 9265241 Review. Serbian.
-
Management of keloids and hypertrophic scars.Am Fam Physician. 2009 Aug 1;80(3):253-60. Am Fam Physician. 2009. PMID: 19621835 Review.
-
Combined modalities in the management of hypertrophic scars and keloids.J Otolaryngol. 1979 Oct;8(5):457-60. J Otolaryngol. 1979. PMID: 501782
-
Management of scar contractures, hypertrophic scars, and keloids.Otolaryngol Clin North Am. 1995 Oct;28(5):1057-68. Otolaryngol Clin North Am. 1995. PMID: 8559572 Review.
-
Treatment of keloids and hypertrophic scars with dermojet injections of bleomycin: a preliminary study.Int J Dermatol. 2005 Sep;44(9):777-84. doi: 10.1111/j.1365-4632.2005.02633.x. Int J Dermatol. 2005. PMID: 16135153 Clinical Trial.
Cited by
-
Liposome associated interferon-alpha-2b functions as an anti-fibrogenic factor in dermal wounds in the guinea pig.Mol Cell Biochem. 2000 May;208(1-2):129-37. doi: 10.1023/a:1007054424400. Mol Cell Biochem. 2000. PMID: 10939636
-
Skin scarring.BMJ. 2003 Jan 11;326(7380):88-92. doi: 10.1136/bmj.326.7380.88. BMJ. 2003. PMID: 12521975 Free PMC article. Review. No abstract available.
-
Impact of pentoxifylline on efficacy, safety, tolerability, and treatment satisfaction of fractional carbon dioxide laser in patients with burn scars: a pilot blinded randomized controlled trial.Lasers Med Sci. 2025 Apr 3;40(1):174. doi: 10.1007/s10103-025-04328-8. Lasers Med Sci. 2025. PMID: 40178694 Clinical Trial.
-
A fibroblast cell line cultured from a hypertrophic scar displays selective downregulation of collagen gene expression: barely detectable messenger RNA levels of the pro alpha 1(III) chain of type III collagen.Arch Dermatol Res. 1995;287(6):534-8. doi: 10.1007/BF00374072. Arch Dermatol Res. 1995. PMID: 7487138
-
[Hyperplastic scars and keloids. Part I: basics and prevention].HNO. 2006 Nov;54(11):893-904; quiz 905. doi: 10.1007/s00106-006-1462-z. HNO. 2006. PMID: 17041777 German.
MeSH terms
Substances
LinkOut - more resources
Medical