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Review
. 2022 Jul;175(7):ITC97-ITC112.
doi: 10.7326/AITC202207190. Epub 2022 Jul 12.

Bipolar Disorder

Mark S Bauer  1
Affiliations
Review

Bipolar Disorder

Mark S Bauer. Ann Intern Med. 2022 Jul.

Abstract

Bipolar disorder (BD) affects approximately 2% of U.S. adults and is the most costly mental health condition for commercial insurers nationwide. Rates of BD are elevated among persons with depression, anxiety disorders, and substance use disorders-conditions frequently seen by primary care clinicians. In addition, antidepressants can precipitate manic or hypomanic symptoms or rapid cycling in persons with undiagnosed BD. Thus, screening in these high-risk groups is indicated. Effective treatments exist, and many can be safely and effectively administered by primary care clinicians.

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