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. 2022 Sep:216:88-91.
doi: 10.1016/j.toxicon.2022.06.011. Epub 2022 Jul 9.

Tetrodotoxin and analogues in two local pufferfish species from Inhaca Island - South of Mozambique: First report in the Mozambican coast

Isidro José Tamele  1 , Ilário Timba  2 , Pedro Reis Costa  3 , Vitor Vasconcelos  4
Affiliations

Tetrodotoxin and analogues in two local pufferfish species from Inhaca Island - South of Mozambique: First report in the Mozambican coast

Isidro José Tamele et al. Toxicon. 2022 Sep.

Abstract

Tetrodotoxins (TTXs) were investigated in two local pufferfish species, Diodon hystrix and Arothron hispidus, from Mozambican coast. TTX and analogues 4-epiTTX, 4,9-anhydroTTX, 11-deoxyTTX, and 11-norTTX-6-(R/S)-ol were found in both species and high level of TTX was found in A. hispidus (9522.0 μg TTX kg-1) than in D. hystrix (350.9 μg TTX kg-1). The distribution of TTX and their analogues in A. hispidus was intestine > liver > skin ≫ muscle > gonads. This is the first report of TTXs in Mozambican coast.

Keywords: Human seafood poisoning; Indian Ocean; Marine toxins monitoring; Mozambican coast; Pufferfish; Tetrodotoxins.

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