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Editorial
. 2022 Jun 27;7(6):541-543.
doi: 10.1016/j.jacbts.2022.04.001. eCollection 2022 Jun.

Migraine and Patent Foramen Ovale: Is Platelet Hyperactivity the Underlying Mechanism?

Robert J Sommer  1 , Barbara T Robbins  1
Affiliations
Editorial

Migraine and Patent Foramen Ovale: Is Platelet Hyperactivity the Underlying Mechanism?

Robert J Sommer et al. JACC Basic Transl Sci. .
No abstract available

Keywords: migraine with aura; oxidative stress; patent foramen oval; platelets; tissue factor.

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Conflict of interest statement

Dr Sommer has a relationship with W.L. Gore & Associates; is the National Cardiology primary investigator on the Gore RELIEF clinical study; was the national coprimary investigator on the ASSURED study; and is currently an investigator in the REDUCE-PAS study. W.L. Gore & Associates provides institutional funding to Columbia University. Dr Robbins has reported that she has no relationships relevant to the contents of this paper to disclose.

Figures

None
Graphical abstract
See this image and copyright information in PMC

Comment on

  • doi: 10.1016/j.jacbts.2022.02.002

References

    1. Bagasse de Dham O. Migraines are a serious problem. Employers can help. Harvard Business Review. February 24, 2021. https://hbr.org/2021/02/migraines-are-a-serious-problem-employers-can-help Accessed April 19, 2022.
    1. Trabeation D., Brambilla M., Canzano P., et al. Migraine in patients undergoing PFO closure: characterization of a platelet-associated pathophysiological mechanism: the LEARNER study. J Am Coll Cardio Basic Trans Science. 2022;7(6):525–540. - PMC - PubMed
    1. Sommer R.J., Nazify T., Privier L., Robbins B.T. Retrospective review of thienopyridine therapy in migraineurs with patent foramen oval. Neurology. 2018;91(22):1002–1009. - PubMed
    1. GORE CARDIOFORM septal occlude migraine clinical study (RELIEF) U.S. National Library of Medicine. https://www.clinicaltrials.gov/ct2/show/NCT04100135?term=RELIEF&cond=Mig... Accessed April 19, 2022.

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