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Editorial
. 2022 Oct 29;75(9):1677-1678.
doi: 10.1093/cid/ciac375.

Are Vancomycin Non-Susceptible Clostridioides difficile Strains Emerging?

Joseph D Lutgring  1 , Susannah L McKay  1 , Amy S Gargis  1 , Alison L Halpin  1 , L Clifford McDonald  1
Affiliations
Editorial

Are Vancomycin Non-Susceptible Clostridioides difficile Strains Emerging?

Joseph D Lutgring et al. Clin Infect Dis. .
No abstract available

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Conflict of interest statement

Potential conflicts of interest . L. C. M. reports participation on a Data Safety Monitoring Board or Advisory Board for NIH/DMID (Protocol 19-0021: A Randomized, Double-blinded Evaluation of CRS3123 in Patients with Non-severe to Severe Clostridium difficile Infection). No funding was received for this letter. The authors: No reported conflicts of interest. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.

Comment in

  • Reply to Lutgring et al.
    Darkoh C, DuPont HL, Arias CA, Oyaro M, Brown EL, Hanson BM. Darkoh C, et al. Clin Infect Dis. 2022 Oct 29;75(9):1678-1679. doi: 10.1093/cid/ciac376. Clin Infect Dis. 2022. PMID: 35818862 No abstract available.

Comment on

References

    1. Darkoh C, Keita K, Odo C, et al. Emergence of clinical Clostridioides difficile isolates with decreased susceptibility to vancomycin. Clin Infect Dis 2022; 74:120–6. - PMC - PubMed
    1. Johnson S, Lavergne V, Skinner AM, et al. Clinical Practice Guideline by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA): 2021 Focused Update Guidelines on Management of Clostridioides difficile infection in adults. Clin Infect Dis 2021; 73:755–7. - PubMed
    1. Suwantarat N, Roberts A, Prestridge J, et al. Comparison of five chromogenic media for recovery of vancomycin-resistant enterococci from fecal samples. J Clin Microbiol 2014; 52:4039–42. - PMC - PubMed
    1. Leeds JA, Sachdeva M, Mullin S, Barnes SW, Ruzin A. In vitro selection, via serial passage, of Clostridium difficile mutants with reduced susceptibility to fidaxomicin or vancomycin. J Antimicrob Chemother 2014; 69:41–4. - PubMed
    1. Clinical and Laboratory Standards Institute (CLSI). Methods for antimicrobial susceptibility testing of anaerobic bacteria, M11, 9th ed. Wayne, PA: CLSI, 2018.

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