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Case Reports
. 2022 Oct;9(5):3625-3629.
doi: 10.1002/ehf2.14060. Epub 2022 Jul 12.

Cardiac arrest as a manifestation of unknown Type V glycogenosis: a case report

Raquel Soria-Navarro  1   2 , Virginia Burgos Palacios  3 , Cristina Castrillo Bustamante  3 , Elena Gallardo Agromayor  4 , Sara Marcos González  5 , Domingo González-Lamuño Leguina  6
Affiliations
Case Reports

Cardiac arrest as a manifestation of unknown Type V glycogenosis: a case report

Raquel Soria-Navarro et al. ESC Heart Fail. 2022 Oct.

Abstract

Few cases have been reported to date, in which a massive rhabdomyolysis causes a cardiac arrest in a male adult suffering from undiagnosed McArdle disease. Veno-arterial extracorporeal membrane oxygenation and cytokine adsorption filter (CytoSorb®) were required to reach a complete and successful recovery.

Keywords: Cardiac arrest; CytoSorb®; ECMO; Exercise intolerance; Myoglobinuria; Myophosphorylase deficiency; Renal failure; Rhabdomyolysis.

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Conflict of interest statement

No conflict of interest.

Figures

Figure 1
Figure 1
ECG performed in emergency department previous to asystole rhythm, showing QRS widening with bizarre QRS morphology and high peaked T waves.
Figure 2
Figure 2
Echocardiogram. (A) TOE (transgastric view) performed during resuscitation manoeuvres. (B) TOE performed after VA‐ECMO implantation. It shows severe left ventricular dysfunction with no regional wall motion abnormalities or hypertrophy. (C) TOE performed after 24 h of VA‐ECMO support revealed significative left ventricular oedema. (D) TTR (parasternal long axis) showed normal biventricular function after VA‐ECMO discontinuation and previous to discharge from hospital.
Figure 3
Figure 3
Skeletal muscle: Biopsy of right deltoids and biceps muscle: histopathological and enzymohistochemical changes lead to early (metabolic) necrosis. (A) Haematoxylin–eosin: moderately affected muscle, made up of muscle fibres of discretely variable sizes; (B) PAS: fibres with absence of staining; (C) DPNH: negative fibres.
See this image and copyright information in PMC

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