Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Jul 13:23:e936315.
doi: 10.12659/AJCR.936315.

Esophagopericardial Fistula and Pneumopericardium as a Complication of Pulmonary Vein Isolation in a 62-Year-Old Man with Atrial Fibrillation: A Case Report

Affiliations
Case Reports

Esophagopericardial Fistula and Pneumopericardium as a Complication of Pulmonary Vein Isolation in a 62-Year-Old Man with Atrial Fibrillation: A Case Report

Ndausung Udongwo et al. Am J Case Rep. .

Abstract

BACKGROUND Pulmonary vein isolation is a method of cardiac ablation therapy used to treat irregular heart rhythm, including atrial fibrillation (AF). This report presents a case of esophagopericardial fistula (EPF) and pneumopericardium as a complication of pulmonary vein isolation in a 62-year-old man with AF. CASE REPORT We report the rare case of a 62-year-old man with a medical history of persistent atrial fibrillation status after ablation 3 days prior to his initial Emergency Department visit for chest pain. Acute coronary syndrome was ruled out with normal electrocardiogram, echocardiography, and troponin tests. Fluid overload and sotalol adverse effects were presumed to be the cause of his symptoms. We discontinued sotalol with diuresis and he was discharged home when his chest pain subsided. Nine days later, he returned to the Emergency Department with worsening similar symptoms and was eventually diagnosed with EPF and pneumopericardium on a computed tomography scan of the chest with contrast. He was managed with esophagogastroduodenoscopy and stent placement along with subxiphoid pericardial window and pericardial drain placement. The patient was discharged in stable condition after removing the pericardial drain. At 10-day and 1-month follow-up, he had no recurrent symptoms. CONCLUSIONS This report shows that although EPF with pneumopericardium is a rare complication of pulmonary vein isolation, it should be rapidly diagnosed and treated as a life-threatening emergency.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: None declared

Figures

Figure 1.
Figure 1.
Computed tomography angiogram of the chest showing pneumopericardium (red arrows in A, B) (green & blue circles in C, D).
Figure 2.
Figure 2.
Endoscopic image showing a 1.5-cm fistula in the distal portion of the esophagus.
Figure 3.
Figure 3.
Fluoroscopic image showing a mid-distal esophageal stent (red arrow).

References

    1. Hindricks G, Potpara T, Dagres N, et al. ESC Scientific Document Group. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): The Task Force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC. Eur Heart J. 2021;42(5):373–498. [Erratum in: Eur Heart J. 2021;42(5):507; Erratum in: Eur Heart J. 2021;42(5):546–47; Erratum in: Eur Heart J. 2021;42(40):4194] - PubMed
    1. Weinmann K, Aktolga D, Pott A, et al. Impact of re-definition of paroxysmal and persistent atrial fibrillation in the 2012 and 2016 European Society of Cardiology atrial fibrillation guidelines on outcomes after pulmonary vein isolation. J Interv Card Electrophysiol. 2021;60(1):115–23. - PMC - PubMed
    1. Veseli G, Iwai S, Jacobson JT. Survival of a patient with an esophagopericar-dial fistula after catheter ablation for atrial fibrillation: a case report and literature review. J Innov Card Rhythm Manag. 2020;11(5):4091–98. - PMC - PubMed
    1. Chavez P, Messerli FH, Casso Dominguez A, et al. Atrioesophageal fistula following ablation procedures for atrial fibrillation: Systematic review of case reports. Open Heart. 2015;2(1):e000257. - PMC - PubMed
    1. Zakaria A, Hipp K, Battista N, et al. Fatal esophageal-pericardial fistula as a complication of radiofrequency catheter ablation. SAGE Open Med Case Rep. 2019;7:2050313. X19841150. - PMC - PubMed

Publication types