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. 2022 Jul;68(7):xxx.
doi: 10.1590/1806-9282.20220259.

Evaluation of the cardioprotective and antihypertensive effect of AVE 0991 in normotensive and hypertensive rats

Matheus Vinicius Barbosa da Silva  1 , Célio Pereira de Sousa Júnior  2 , Heverton Valentim Colaço da Silva  1 , Vanessa Maria Dos Santos  3 , Francisco Israel Magalhães Feijao  4 , Amanda de Oliveira Bernardino  1 , José Augusto Calafell Roig Tiburcio de Melo  5
Affiliations

Evaluation of the cardioprotective and antihypertensive effect of AVE 0991 in normotensive and hypertensive rats

Matheus Vinicius Barbosa da Silva et al. Rev Assoc Med Bras (1992). 2022 Jul.
No abstract available

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Conflict of interest statement

Conflicts of interest: the authors declare there is no conflicts of interest.

Figures

Figure 1
Figure 1. Actions generated by the ligation of AVE 0991 on the MAS receiver. Ang-II is converted to Ang-(1-7) by ACE2. Binding of Ang-(1-7) or other agonists, such as AVE 0991, on MAS receptors, generates effects contrary to those of binding of Ang-II on AT1 receptor.
Figure 2
Figure 2. Flowchart of the article selection process.
See this image and copyright information in PMC

References

    1. Magder S. The meaning of blood pressure. Crit Care. 2018;22(1):251–251. doi: 10.1186/s13054-018-2171-1. - DOI - PMC - PubMed
    1. Jordan J, Kurschat C, Reuter H. Arterial hypertension. Dtsch Ärztebl Int. 2018;115:557–568. doi: 10.3238/arztebl.2018.0557. - DOI - PMC - PubMed
    1. Hering D, Trzebski A, Narkiewicz K. Recent advances in the pathophysiology of arterial hypertension – potential implications for clinical practice. Pol Arch Intern Med. 2017;127(3):195–204. doi: 10.20452/pamw.3971. - DOI - PubMed
    1. IE K. Arterial hypertension. Hellenic J Cardiol. 2013;54(5):413–415. - PubMed
    1. DeGuire J. Blood pressure and hypertension. Health Rep. 2019;30(2):14–21. doi: 10.25318/82-003-x201900200002. - DOI - PubMed