DCs unchained: Whetting dendritic-cell appetite boosts wound healing
- PMID: 35830825
- DOI: 10.1016/j.immuni.2022.06.008
DCs unchained: Whetting dendritic-cell appetite boosts wound healing
Abstract
Apoptotic-cell uptake (efferocytosis) by dendritic cells (DCs) has been mainly linked to their antigen presentation property. In a recent issue of Nature, Maschalidi et al. identified a break to efferocytosis in DCs, the inhibition of which improves skin debris cleansing after a wound, accelerating healing.
Copyright © 2022 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes.Nature. 2022 Jun;606(7915):776-784. doi: 10.1038/s41586-022-04754-6. Epub 2022 May 25. Nature. 2022. PMID: 35614212
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