Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Feb 16;10(2):40-46.
doi: 10.4103/jmau.jmau_74_20. eCollection 2022 Apr-Jun.

Different Cells of the Human Body: Categories and Morphological Characters

Affiliations
Review

Different Cells of the Human Body: Categories and Morphological Characters

Hany K K Mostafa. J Microsc Ultrastruct. .

Abstract

The cell is the basic structural unit of all living organisms. Most of the cells forming the human body share the basic components, but there are many categories that have specific light and electron microscopic characteristics. This review shed a light on these cell categories and their morphologies. Stem cell category is the cells responsible for the regeneration of damaged or lost cells, whereas protein-secreting cells are those responsible for the production and secretion of proteins. Protein-secreting cells have specific characters such as basophilic cytoplasm and vesicular nucleus by light microscope; these are confirmed by an electron microscope that shows rough endoplasmic reticulum, Golgi apparatus, secretory granules, and mitochondria. Steroid secreting, ion transporting, and contracting categories have specific morphology. Phagocytic cells such as macrophages and neutrophils are characterized by the presence of many lysosomes and phagosomes. Supporting cells are very important category as they not only support but also usually have another function such as myelin formation in Schwann, blood-brain barrier in astrocytes, or modification of response as in Pacinian corpuscle. Many cells showed interrelated characters between different categories, for example, phagocytic cells are able to contract to perform their function in fighting microorganism. Although we have trillions of cells, yet they only fall in some categories. Each cell category has specific morphological characters confirmed by ultrastructural characters. They all adapted to perform the desired functions.

Keywords: Categories; cells; human body; morphology.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
The EM of goblet cell with microvilli (M), rough endoplasmic reticulum (R), Golgi complex (G), and secretory granules (SG)[2]
Figure 2
Figure 2
Steroid-secreting cells with the smooth endoplasmic reticulum, mitochondria (M), and lipid droplets (L)[2]
Figure 3
Figure 3
Keratinocytes in different layers stratum basale (B), stratum spinosum (S), granulosum (G), corneum (C), dermis (D)[2]
Figure 4
Figure 4
Supporting cells of taste bud[2]

Similar articles

Cited by

References

    1. Bianconi E, Piovesan A, Facchin F, Beraudi A, Casadei R, Frabetti F, et al. An estimation of the number of cells in the human body. Ann Hum Biol. 2013;40:463–71. - PubMed
    1. Mescher AL Junqueira LC. Junqueira’s Basic Histology: Text and Atlas. 2018
    1. Alberts, Bruce, Alexander D, Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter. Molecular Biology of the Cell. Sixth edition. New York, NY: W. W. Norton & Company; 2014.
    1. Gartner LP. 7th ed. Philadelphia: Wolters Kluwer; 2018. Color Atlas and Text of Histology.
    1. Ross MH, Pawlina W. 7th ed. China: Wolters Kluwer Health; 2016. Histology: A Text and Atlas : With Correlated Cell and Molecular Biology.