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. 2022 Jul 10;83(3):e80-e82.
doi: 10.1055/s-0042-1753519. eCollection 2022 Jul.

Esthesioneuroblastoma (Olfactory Neuroblastoma): Overview and Extent of Surgical Approach and Skull Base Resection

Emily E Karp  1 , Jamie J Van Gompel  1   2 , Garret Choby  1   2
Affiliations

Esthesioneuroblastoma (Olfactory Neuroblastoma): Overview and Extent of Surgical Approach and Skull Base Resection

Emily E Karp et al. J Neurol Surg Rep. .

Abstract

Esthesioneuroblastoma is a rare malignancy originating from the olfactory epithelium. Treatment consists of surgical resection with strong consideration for adjuvant treatment in advanced Kadish stage and high Hyams grade. In the modern era, overall outcomes for esthesioneuroblastoma are favorable compared with many other sinonasal malignancies with 5-year overall survival estimated to be 80%. When selecting the optimal surgical approach, the surgeon must consider the approach that will allow for a negative margin resection and adequate reconstruction. In appropriately selected patients, endoscopic outcomes appear at least equivalent to open approaches and unilateral endoscopic approach may be used in select olfactory preservation cases.

Keywords: craniofacial resection; endoscopic; esthesioneuroblastoma; neuroblastoma; olfactory.

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Conflict of interest statement

Conflict of Interest None declared.

Figures

Fig. 1
Fig. 1
( A ) Case presentation of coronal magnetic resonance imaging, T1 postgadolinium. ( B ) Arrow indicates contralateral olfactory tract involvement.
Fig. 2
Fig. 2
Endoscopic bilateral craniofacial resection.
See this image and copyright information in PMC

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