Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jun 27:9:922063.
doi: 10.3389/fmed.2022.922063. eCollection 2022.

Global Research Trends in Irritable Bowel Syndrome: A Bibliometric and Visualized Study

Tai Zhang  1   2 , Xiangxue Ma  1   2 , Wende Tian  1   3 , Jiaqi Zhang  1   2 , Yuchen Wei  1   2 , Beihua Zhang  1   2 , Fengyun Wang  1   2 , Xudong Tang  4
Affiliations

Global Research Trends in Irritable Bowel Syndrome: A Bibliometric and Visualized Study

Tai Zhang et al. Front Med (Lausanne). .

Abstract

Background: There are about 10-23% of adults worldwide suffering from irritable bowel syndrome (IBS). Over the past few decades, there are many aspects of uncertainty regarding IBS leading to an ongoing interest in the topic as reflected by a vast number of publications, whose heterogeneity and variable quality may challenge researchers to measure their scientific impact, to identify collaborative networks, and to grasp actively researched themes. Accordingly, with help from bibliometric approaches, our goal is to assess the structure, evolution, and trends of IBS research between 2007 and 2022.

Methods: The documents exclusively focusing on IBS from 2007 to 2022 were retrieved from the Science Citation Index Expanded of the Web of Science Core Collection. The annual productivity of IBS research, and the most prolific countries or regions, authors, journals and resource-, intellectual- and knowledge-sharing in IBS research, as well as co-citation analysis of references and keywords were analyzed through Microsoft Office Excel 2019, CiteSpace, and VOSviewer.

Results: In total, 4,092 publications were reviewed. The USA led the list of countries with the most publications (1,226, 29.96%). Mayo Clinic contributed more publications than any other institution (193, 4.71%). MAGNUS SIMREN stood out as the most active and impactful scholar with the highest number of publications and the greatest betweenness centrality value. The most high-yield journal in this field was Neurogastroenterology and motility: the official journal of the European Gastrointestinal Motility Society (275, 6.72%). Gastroenterology had the most co-citations (3,721, 3.60%). Keywords with the ongoing strong citation bursts were chromogranin A, rat model, peptide YY, gut microbiota, and low-FODMAP diet, etc.

Conclusion: Through bibliometric analysis, we gleaned deep insight into the current status of literature investigating IBS for the first time. These findings will be useful to scholars interested in understanding the key information in the field, as well as identifying possible research frontiers.

Keywords: CiteSpace; VOSviewer; bibliometrics; hot topics; irritable bowel syndrome; trends.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
The number of articles published annually in IBS research.
FIGURE 2
FIGURE 2
Network of countries and regions engaged in IBS research.
FIGURE 3
FIGURE 3
Network of institutions engaged in IBS research.
FIGURE 4
FIGURE 4
Network of authors in IBS research.
FIGURE 5
FIGURE 5
Top 25 references with strong citation bursts in IBS research.
FIGURE 6
FIGURE 6
Map of keyword clustering with a minimum of 5 occurrences in IBS.
FIGURE 7
FIGURE 7
The timeline view of keywords in IBS research.
FIGURE 8
FIGURE 8
The keyword clustering knowledge map of IBS research.
FIGURE 9
FIGURE 9
Keywords with strong citation bursts in IBS research.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Enck P, Aziz Q, Barbara G, Farmer AD, Fukudo S, Mayer EA, et al. Irritable bowel syndrome. Nat Rev Dis Primers. (2016) 2:16014. 10.1038/nrdp.2016.14 - DOI - PMC - PubMed
    1. Sperber AD, Dumitrascu D, Fukudo S, Gerson C, Ghoshal UC, Gwee KA, et al. The global prevalence of IBS in adults remains elusive due to the heterogeneity of studies: a Rome Foundation working team literature review. Gut. (2017) 66:1075–82. 10.1136/gutjnl-2015-311240 - DOI - PubMed
    1. Lovell RM, Ford AC. Global prevalence of and risk factors for irritable bowel syndrome: a meta-analysis. Clin Gastroenterol Hepatol. (2012) 10:712–21.e4. 10.1016/j.cgh.2012.02.029 - DOI - PubMed
    1. Canavan C, West J, Card T. The epidemiology of irritable bowel syndrome. Clin Epidemiol. (2014) 6:71–80. 10.2147/CLEP.S40245 - DOI - PMC - PubMed
    1. Schmulson MJ, Drossman DA. What Is New in Rome IV. J Neurogastroenterol Motil. (2017) 23:151–63. 10.5056/jnm16214 - DOI - PMC - PubMed