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Case Reports
. 2022 Nov;87(5):455-457.
doi: 10.1111/cod.14188. Epub 2022 Jul 22.

Allergic contact dermatitis caused by octylisothiazolinone in a leather car seat: Case report and emergence of octylisothiazolinones in leather goods in Switzerland

Affiliations
Case Reports

Allergic contact dermatitis caused by octylisothiazolinone in a leather car seat: Case report and emergence of octylisothiazolinones in leather goods in Switzerland

Yassaman Alipour Tehrany et al. Contact Dermatitis. 2022 Nov.
No abstract available

Keywords: CAS no. 26530-20-1; allergic contact dermatitis; leather; methylisothiazolinone; octylisothiazolinone; preservative.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
(A) Well‐demarcated eczematous lesions on the upper back, shoulders and arms. (B) Patch tests positive for OIT (++) and leather car seat samples (++) at D4

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References

    1. Aerts O, Meert H, Romaen E, et al. Octylisothiazolinone, an additional cause of allergic contact dermatitis caused by leather: case series and potential implications for the study of cross‐reactivity with methylisothiazolinone. Contact Dermatitis. 2016;75:276‐284. - PubMed
    1. Hunt WTN, Dunnill MG, Sansom JE. Sofa dermatitis again? A case report of allergic contact dermatitis to octylisothiazolinone from a leather reclining chair. Contact Dermatitis. 2020;82:161‐162. - PubMed
    1. Alipour Tehrany Y, Quenan S, Bugey A, Piletta P. Allergic contact dermatitis caused by octylisothiazolinone in a leather sofa. Contact Dermatitis. 2018;79:188‐189. - PubMed
    1. Kim D, Kim EH, Choi S, et al. A commonly used biocide 2‐N‐octyl‐4‐isothiazolin‐3‐oneInduces blood‐brain barrier dysfunction via cellular thiol modification and mitochondrial damage. Int J Mol Sci. 2021;22:2563. - PMC - PubMed

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