Ferroptosis: A novel pathological mechanism of aortic dissection

Affiliations

¹ Division of Cardiothoracic and Vascular Surgery, Sino-Swiss Heart-Lung Transplantation Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
² Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
³ Division of Cardiothoracic and Vascular Surgery, Sino-Swiss Heart-Lung Transplantation Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Organ Transplantation,Ministry of Education, NHC Key Laboratory of Organ Transplantation, Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei, China. Electronic address: xiangwei@tjh.tjmu.edu.cn.
⁴ Division of Cardiothoracic and Vascular Surgery, Sino-Swiss Heart-Lung Transplantation Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Organ Transplantation,Ministry of Education, NHC Key Laboratory of Organ Transplantation, Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei, China. Electronic address: jds@hust.edu.cn.

Comment

Yue Chen et al. Pharmacol Res. 2022 Aug.

. 2022 Aug:182:106351.

doi: 10.1016/j.phrs.2022.106351. Epub 2022 Jul 12.

¹ Division of Cardiothoracic and Vascular Surgery, Sino-Swiss Heart-Lung Transplantation Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
² Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
³ Division of Cardiothoracic and Vascular Surgery, Sino-Swiss Heart-Lung Transplantation Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Organ Transplantation,Ministry of Education, NHC Key Laboratory of Organ Transplantation, Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei, China. Electronic address: xiangwei@tjh.tjmu.edu.cn.
⁴ Division of Cardiothoracic and Vascular Surgery, Sino-Swiss Heart-Lung Transplantation Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Organ Transplantation,Ministry of Education, NHC Key Laboratory of Organ Transplantation, Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei, China. Electronic address: jds@hust.edu.cn.

No abstract available

Keywords: Aortic dissection; BRD4770; Ferroptosis; Inflammation; Liproxstatin-1; Smooth muscle cell.

Comment on

BRD4770 functions as a novel ferroptosis inhibitor to protect against aortic dissection.
Chen Y, Yi X, Huo B, He Y, Guo X, Zhang Z, Zhong X, Feng X, Fang ZM, Zhu XH, Wei X, Jiang DS. Chen Y, et al. Pharmacol Res. 2022 Mar;177:106122. doi: 10.1016/j.phrs.2022.106122. Epub 2022 Feb 8. Pharmacol Res. 2022. PMID: 35149187
Ferroptosis in aortic dissection: Cause or effect.
Song W, Chen J, Wei L. Song W, et al. Pharmacol Res. 2022 Aug;182:106344. doi: 10.1016/j.phrs.2022.106344. Epub 2022 Jul 6. Pharmacol Res. 2022. PMID: 35809765 No abstract available.