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Review
. 2025 Apr;68(3):545-555.
doi: 10.1007/s10840-022-01299-6. Epub 2022 Jul 14.

Transvenous or subcutaneous implantable cardioverter defibrillator: a review to aid decision-making

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Review

Transvenous or subcutaneous implantable cardioverter defibrillator: a review to aid decision-making

Milena Leo et al. J Interv Card Electrophysiol. 2025 Apr.

Abstract

The implantable cardioverter-defibrillator (ICD) is a proven treatment for preventing sudden cardiac death. Transvenous leads are associated with significant mortality and morbidity, and the subcutaneous ICD (S-ICD) addresses this. However, it is not without limitations, in particular the absence of anti-tachycardia pacing. The decision of which device is most suitable for an individual patient is often complex. Here, we review the relative merits and weaknesses of both the transvenous and S-ICD. We summarise the available evidence for each device in particular patient cohorts, namely: ischaemic and non-ischaemic cardiomyopathy, idiopathic ventricular fibrillation, Brugada syndrome, long QT syndrome, arrhythmogenic right ventricular cardiomyopathy, and hypertrophic cardiomyopathy.

Keywords: Implantable cardioverter-defibrillator; Subcutaneous ICD; Sudden cardiac death; Transvenous ICD; Ventricular arrhythmias.

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Conflict of interest statement

Declarations. Ethics approval: Not applicable. Informed consent: Not applicable. Conflict of interest: The authors declare no competing interests.

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