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Review
. 2022 Jul 8:16:89-105.
doi: 10.2147/BTT.S368152. eCollection 2022.

Promising Stem Cell therapy in the Management of HIV and AIDS: A Narrative Review

Usha Rani Kandula  1 , Addisu Dabi Wake  1
Affiliations
Review

Promising Stem Cell therapy in the Management of HIV and AIDS: A Narrative Review

Usha Rani Kandula et al. Biologics. .

Abstract

Stem cell therapies are becoming a major topic in biomedical research all over the planet. It may be a viable treatment choice for people suffering from a wide range of illnesses and injuries. It has recently emerged as an extremely intriguing and well-established science and research topic. Expectations have risen due to advancements in therapeutic approaches. Multiple laboratory testing of regulated stem cell culture and derivation is carried out before the formation of stem cells for the use of therapeutic process. Whereas HIV infection is contagious and can last a lifetime. Researchers are still working to develop a comprehensive and effective treatment for HIV and its associated condition, as well as AIDS. HIV propagation is primarily restricted to the immune system, notably T lymphocytes, as well as macrophages. Large numbers of research studies have contributed to a plethora of data about the enigmatic AIDS life cycle. This vast amount of data provides potential targets for AIDS therapies. Currently, stem cell transplantation, along with other procedures, provided novel insights into HIV pathogenesis and offered a glimpse of hope for the development of a viable HIV cure technique. One of its existing focus areas in HIV and AIDS research is to develop a novel therapeutic strategic plan capable of providing life-long complete recovery of HIV and AIDS without regular drug treatment and, inevitably, curative therapy for HIV and AIDS. The current paper tries to address the possibilities for improved stem cell treatments with "bone marrow, Hematopoietic, human umbilical cord mesenchymal, Genetical modifications with CRISPR/Cas9 in combination of stem cells, induced pluripotent stem cells applications" are discussed which are specifically applied in the HIV and AIDS therapeutic management advancement procedures.

Keywords: HIV and AIDS advancements; HIV/AIDS Management; stem cell genetic applications/modifications; stem cell in clinical practices; stem cell therapy.

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Conflict of interest statement

The authors declare that they have no conflicts of interest in relation to this work.

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