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Editorial
. 2022 Jun 28:16:965406.
doi: 10.3389/fnins.2022.965406. eCollection 2022.

Editorial: Methods on the Assessment of Human Baroreflex Function

Yue-Der Lin  1   2 , André Diedrich  3   4
Affiliations
Editorial

Editorial: Methods on the Assessment of Human Baroreflex Function

Yue-Der Lin et al. Front Neurosci. .
No abstract available

Keywords: autonomic nervous system; baroreflex; blood pressure; heart rate; sympathetic activity; vagal activity.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Simplified anatomical and functional scheme of baroreflex function. Baroreceptors in the carotid sinus, aortic arch, right atrium and in the cardiopulmonary veins are activated-by (1) stretching and passing this information through the Vagus (X) or glossopharyngeal (IX) nerves to (2) the nucleus tractus solitarii (NTS) of the brain stem. The NTS projects to neurons in caudal ventrolateral medulla (CVLM) which (3) inhibits sympathetic pacemaker neurons in the rostral ventrolateral medulla (RVLM) and (4) reduces sympathetic outflow. This decreases heart rate, cardiac output, and (5) blood pressure. Activation of the NTS projects also to the nucleus ambiguous (NA) and dorsal motor nucleus of the Vagus (DMNV) and increases parasympathetic activity. Common methods to evaluate baroreflex function include (A) pharmacological challenge with vasoactive drugs, (B) spontaneous sequence analysis, (C) spectral analysis, (D) measurements of catecholamines, or (E) muscle sympathetic activity (MSNA) during orthostatic challenges.
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References

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