Higher than predicted resting energy expenditure and lower physical activity in healthy underweight Chinese adults

Sumei Hu¹, Xueying Zhang², Marina Stamatiou³, Catherine Hambly³, Yumeng Huang⁴, Jianfang Ma⁴, Yiran Li⁵, John R Speakman⁶

Affiliations

¹ Shenzhen Key Laboratory of Metabolic Health, Center for Energy Metabolism and Reproduction, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, PRC; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, PRC; Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Engineering and Technology Research Center of Food Additives, National Soybean Processing Industry Technology Innovation Center, Beijing Technology and Business University, Beijing 100048, PRC.
² Shenzhen Key Laboratory of Metabolic Health, Center for Energy Metabolism and Reproduction, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, PRC; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, PRC; School of Biological Sciences, University of Aberdeen, Aberdeen, AB24 2TZ, Scotland, UK.
³ School of Biological Sciences, University of Aberdeen, Aberdeen, AB24 2TZ, Scotland, UK.
⁴ Department of Neurology, Institute of Neurology, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, Shanghai, PRC.
⁵ College of Biology, China Agricultural University, Beijing, PRC.
⁶ Shenzhen Key Laboratory of Metabolic Health, Center for Energy Metabolism and Reproduction, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, PRC; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, PRC; School of Biological Sciences, University of Aberdeen, Aberdeen, AB24 2TZ, Scotland, UK; CAS Center for Excellence in Animal Evolution and Genetics (CCEAEG), Kunming, PRC. Electronic address: j.speakman@abdn.ac.uk.

PMID: 35839758
DOI: 10.1016/j.cmet.2022.05.012

Free article

Higher than predicted resting energy expenditure and lower physical activity in healthy underweight Chinese adults

Sumei Hu et al. Cell Metab. 2022.

Free article

. 2022 Oct 4;34(10):1413-1415.

doi: 10.1016/j.cmet.2022.05.012. Epub 2022 Jul 14.

Authors

Sumei Hu¹, Xueying Zhang², Marina Stamatiou³, Catherine Hambly³, Yumeng Huang⁴, Jianfang Ma⁴, Yiran Li⁵, John R Speakman⁶

Affiliations

¹ Shenzhen Key Laboratory of Metabolic Health, Center for Energy Metabolism and Reproduction, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, PRC; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, PRC; Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Engineering and Technology Research Center of Food Additives, National Soybean Processing Industry Technology Innovation Center, Beijing Technology and Business University, Beijing 100048, PRC.
² Shenzhen Key Laboratory of Metabolic Health, Center for Energy Metabolism and Reproduction, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, PRC; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, PRC; School of Biological Sciences, University of Aberdeen, Aberdeen, AB24 2TZ, Scotland, UK.
³ School of Biological Sciences, University of Aberdeen, Aberdeen, AB24 2TZ, Scotland, UK.
⁴ Department of Neurology, Institute of Neurology, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, Shanghai, PRC.
⁵ College of Biology, China Agricultural University, Beijing, PRC.
⁶ Shenzhen Key Laboratory of Metabolic Health, Center for Energy Metabolism and Reproduction, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, PRC; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, PRC; School of Biological Sciences, University of Aberdeen, Aberdeen, AB24 2TZ, Scotland, UK; CAS Center for Excellence in Animal Evolution and Genetics (CCEAEG), Kunming, PRC. Electronic address: j.speakman@abdn.ac.uk.

PMID: 35839758
DOI: 10.1016/j.cmet.2022.05.012

Abstract

Contrary to popular opinion that lean individuals "eat what they want" and exercise more, Hu et al. study a cohort of healthy underweight volunteers and reveal them to have reduced physical activity relative to normal BMI controls and lower food intake. This cohort is also shown to have higher than expected resting energy expenditure, which is associated with elevations in thyroid hormones.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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Higher than predicted resting energy expenditure and lower physical activity in healthy underweight Chinese adults

Affiliations

Higher than predicted resting energy expenditure and lower physical activity in healthy underweight Chinese adults

Authors

Affiliations

Abstract

Conflict of interest statement

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LinkOut - more resources

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