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Comment
. 2022 Jul;607(7920):647.
doi: 10.1038/d41586-022-01951-1.

CRISPR 'cousin' put to the test in landmark heart-disease trial

Heidi Ledford
Comment

CRISPR 'cousin' put to the test in landmark heart-disease trial

Heidi Ledford. Nature. 2022 Jul.
No abstract available

Keywords: CRISPR-Cas9 genome editing; Gene therapy; Medical research.

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Comment on

  • In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates.
    Musunuru K, Chadwick AC, Mizoguchi T, Garcia SP, DeNizio JE, Reiss CW, Wang K, Iyer S, Dutta C, Clendaniel V, Amaonye M, Beach A, Berth K, Biswas S, Braun MC, Chen HM, Colace TV, Ganey JD, Gangopadhyay SA, Garrity R, Kasiewicz LN, Lavoie J, Madsen JA, Matsumoto Y, Mazzola AM, Nasrullah YS, Nneji J, Ren H, Sanjeev A, Shay M, Stahley MR, Fan SHY, Tam YK, Gaudelli NM, Ciaramella G, Stolz LE, Malyala P, Cheng CJ, Rajeev KG, Rohde E, Bellinger AM, Kathiresan S. Musunuru K, et al. Nature. 2021 May;593(7859):429-434. doi: 10.1038/s41586-021-03534-y. Epub 2021 May 19. Nature. 2021. PMID: 34012082

References

    1. Musunuru, K. et al. Nature 593, 429–434 (2021). - PubMed - DOI
    1. Rothgangl, T. et al. Nature Biotechnol. 39, 949–957 (2021). - PubMed - DOI

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