Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Jul 15;17(1):60.
doi: 10.1186/s13000-022-01236-1.

Breast cancer combined with contralateral neck lymph node metastasis: a case report

Xiaoxiao Zhong #  1 , Fengjiao Ding #  1 , Liyuan Qian  1 , Wei Wu  1 , Yanguang Wen  1 , Boni Ding  2
Affiliations
Case Reports

Breast cancer combined with contralateral neck lymph node metastasis: a case report

Xiaoxiao Zhong et al. Diagn Pathol. .

Abstract

Background: Contralateral neck lymph node metastasis is rare in primary breast cancer. Its clinical staging and treatment principles lack authoritative guidelines. A case of a 30-year-old breast cancer patient with contralateral neck lymph node metastasis is presented. The clinical treatment is discussed in combination with current research.

Case presentation: A 30-year-old woman presented with a right breast mass for 5 months and left neck lymph node enlargement for 5 days. Mammography showed a 33 mm*14.3 mm mass in the inner quadrant of the right breast. The ultrasound showed several hypoechoic nodules on the left side of the neck. Rapid intraoperative pathological examination diagnosed a right breast malignant tumor and poorly differentiated carcinoma of the left cervical lymph nodes. Then, right mastectomy was performed immediately. The patient was scheduled to undergo chemotherapy, molecular targeted therapy, radiotherapy and endocrine therapy after the operation. The long-term efficacy remains to be seen.

Conclusion: The infrequent presentation of breast cancer with metastasis to the contralateral neck lymph node can be challenging for standard therapies.

Keywords: Breast cancer; Case report; Contralateral neck lymph node metastasis; Treatment.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Fig. 1
Fig. 1
Whole-body PET-CT: There were high metabolic lymph nodes in the left neck and high metabolic nodules on the left side of the sternum stem
Fig. 2
Fig. 2
Postoperative pathological section of the right breast (A, B: H&E. 200×): invasive ductal carcinoma, grade III. Pathological section of the left neck lymph node after surgery (C: H&E. 40×; D: H&E. 100×): cancer metastasis can be seen
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Gradishar WJ, Anderson BO, Abraham J, et al. Breast Cancer, version 3.2020, NCCN clinical practice guidelines in oncology. J Natl Compr Cancer Netw. 2020;18(4):452–478. doi: 10.6004/jnccn.2020.0016. - DOI - PubMed
    1. Giuliano AE, Connolly JL, Edge SB, et al. Breast Cancer-major changes in the American joint committee on Cancer eighth edition cancer staging manual [published correction appears in CA Cancer J Clin. 2017 Jul 8;67(4):345]. CA Cancer J Clin 2017;67(4):290–303. - PubMed
    1. Pagani O, Senkus E, Wood W, et al. International guidelines for management of metastatic breast cancer: can metastatic breast cancer be cured? J Natl Cancer Inst. 2010;102(7):456–463. doi: 10.1093/jnci/djq029. - DOI - PMC - PubMed
    1. Pan H, Wang H, Qian M, et al. Comparison of survival outcomes among patients with breast cancer with distant vs ipsilateral supraclavicular lymph node metastases. JAMA Netw Open. 2021;4(3):1809. - PMC - PubMed
    1. Nagarkar R, Wagh A, Kokane G, et al. Cervical lymph nodes: a hotbed for metastasis in malignancy. Indian J Otolaryngol Head Neck Surg. 2019;71:976–980. doi: 10.1007/s12070-019-01664-4. - DOI - PMC - PubMed

Publication types