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Comment
. 2022 Jul 16;7(1):237.
doi: 10.1038/s41392-022-01092-x.

Restored oligodendrogenesis by fibroblast growth factor 17: molecular mechanism for rejuvenating ageing-related memory deficit

Xiao-Yi Xiong  1 , Alexey Semyanov  2   3 , Yong Tang  4   5
Affiliations
Comment

Restored oligodendrogenesis by fibroblast growth factor 17: molecular mechanism for rejuvenating ageing-related memory deficit

Xiao-Yi Xiong et al. Signal Transduct Target Ther. .
No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Mechanism of Young CSF or Fgf17 infusion mediated oligodendrogenesis. OPC proliferation and differentiation (termed oligodendrogenesis) were inhibited with age. Young CSF or the brain-specific growth factor Fgf17 infusion boosts hippocampal oligodendrogenesis via reactivating SRF signaling pathway and improved the long-term memory recall of aged mice
See this image and copyright information in PMC

Comment on

  • Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17.
    Iram T, Kern F, Kaur A, Myneni S, Morningstar AR, Shin H, Garcia MA, Yerra L, Palovics R, Yang AC, Hahn O, Lu N, Shuken SR, Haney MS, Lehallier B, Iyer M, Luo J, Zetterberg H, Keller A, Zuchero JB, Wyss-Coray T. Iram T, et al. Nature. 2022 May;605(7910):509-515. doi: 10.1038/s41586-022-04722-0. Epub 2022 May 11. Nature. 2022. PMID: 35545674 Free PMC article.

References

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