Laboratory scale medicinal plants mediated green synthesis of biocompatible nanomaterials and their versatile biomedical applications

Abstract

Nanoparticles and its green synthesis with plants have become an important field of nanoscience due it is great benefits provided to humanity through it and its cost effective, least harm to humans and the environment also, it offering a lot of application in biomedical research, diagnostics, and medicine as well as, drug manufacturing, improvement, or drug discovery. In this work, I focused on green synthesis nanoparticles with antioxidant involve in plants and the method for preparing them also the factors on which the extraction process depends on, spectroscopic techniques like UV-Visible, (TEM), (XRD), (IR), (EDX), (SEM), (HPLC), and zeta potential are use here.

Keywords: Applications; Characterization; Green synthesis; Nanoparticles; Nanotechnology.

Graphical abstract

Fig. 1

Scheme Plants Mediated Green Synthesis of Nanomaterials and their Versatile Applications.

Fig. 2

Inhibitory activity of synthesized PtNPs of Ajwa and PtNPs of Barni against human (HCT-116) cell line, (HepG-2) cell line and (MCF-7) cell line.

Fig. 3

A) The photo image of coloncarcinoma cells (HCT-116) treatment by PtNPs of Ajwa and Barni, B) The photo image of Hepatocellularcarcinoma cells (HepG-2) treatment by PtNPs of Ajwa and Barni, C) The photo image of breastcarcinoma cells (MCF-7) treatment by PtNPs of Ajwa and Barni.

Fig. 4

A) AuNPs percent cell viability B) AuNPs percent inhibition C) MCF-7, HePG-2 and HCT-116 cell lines inhibition by AuNPs, D) Chemical structure of secoisolariciresinoldiglucoside (SDG).

Fig. 5

Molecular interactions of A) Linamarin, B) Lotaustralin, C) linustatin, D) neolinustatin, E) SDG to MCF-7 active sites.

Fig. 6

Antioxidant ABTS and DPPH Activity of AuNPs and Flaxseed Extract.

Fig. 7

AuNPs Fibrinolytic Activity of A) Licorice root and B) Flaxseed extract.

Fig. 8

A) Color transformation of AuNPs of different sizes, B) Color of silver nanoparticles, C) Azadirachta indica Mediated Biosynthesis of Silver Nanoparticles.

Fig. 9

A) Biosynthesis of Turmeric Mediated Ag-NPs B) Vitex Negundo L Mediated Biosynrhesis of Ag-NPs and its Antibacterial Properties C) Green production and antibacterial activity of Boerhaavia diffusa Mediated Ag-NPs.

Fig. 10

A) Biosynthesis of Azadirachta indica Mediated Pt-NPs B) Quercus Glauca mediated Pt-NPs and its electrochemical hydrazine oxidation in water, C) Biosynthesis of Ocimum sanctum (Tulsi Mediated Pt-NPs.

Fig. 11

A) TEM micrograph of Pt-NPs at a-4 ml, b-5 ml, and c-6 ml Anbara extract (25) °C, B) Anbara extract (6) ml and (10–3) M (H₂PtCl₆·6H₂O) stock solutions (a) 2 ml (b) 3 ml, and (c) 4 ml, after (7) hours at (25) °C, C) TEM micrograph of (Pt-NPs) (4) ml of (H₂PtCl₆) solution and (6) ml of Anbara extract at different time a: (4) hrs, b (7) hrs, c (11) hrs at (25) °C.

Fig. 12

A) X-Ray diffraction pattern of (Pt-NPs) prepared with aqueous Ajwa extract, B) With Licorice root extract, XRD spectrum of Au-NPs, C) XRay diffraction pattern of Ag-CsL., (NPs).

Fig. 13

A) FTIR spectra of the dried Ajwa and capped (Pt-NPs) using the Ajwa extract, B) FTIR spectra of (Au-NPs) (b) and Licorice root extract (a), C) FTIR spectra of (A) the dried Cynara scolymus L., and (B) capped (Ag-NPs) using the Cynara scolymus L., extract.

Fig. 14

A) EDX analysis of Licorice root@AuNPs, B)SEM Micrograph of Au-NPs.

Fig. 15

A) HPLC chromatograms of Phenolics (a), flavonoids (b), carotenoids (c), Organic acids (d), glycosides (e) in flaxseed, B) HPLC charts for a) non-essential and b) essential amino acid separation in Flaxseed extract.

Fig. 16

HPLC chromatograms of water soluble vitamins (a) fat soluble vitamins (b) of flaxseed.

Fig. 17

(A) Chart for Separation of fatty acids in flaxseed and (B) Mass Fragmentation of the separated of Linoleic (a), Palmitic (b), Oleic (c), Linolenic (d), Stearic (e).

Fig. 18

(A) DLS image (a) and (ZP) (b) of (Au-NPs) synthesized by Licorice root extract, B) corresponding size distribution graph (A) and (ZP) (B) of (Fs-Au-NPs).